Hello, my dad has PC stage IV met to bladder and liver
10-10-19 My dad got a bed and a opportunity to be seen by Dr Nancy Dawson at Georgetown , she recommend chemotherapy right away due to the aggressiveness of the PC. They control the pain in liver due to tumors are growing and stretching out the liver. No more catheter for the bladder but still peeing every 20 minutes and no blood.
10-12-19 got first dose of Chemo
10-14-19 having nausea and fatigue, controlled with palliative pills
10-17-19 got discharge from hospital due to he has the second chemo in other hospital close to his home.
10-18-19 He could not get chemo due to he was too weak and kept vomiting, he got admitted to ER
Stayed in the hospital till feel better for second dose.
10-31-19 Got second chemo and got discharge the next day.
11-06-19 Appointment with the Dr and he could not get the third chemo due to he was too weak.
Attached is the liver test like AST, ALT that i keep tracking and the PSA test:
8-1-19 50.3 ( when he got diagnosed )
9-23-19 474
10-22-19 833.5
Dont know why is increasing the PSA so fast when he got already 2 lupron injection and 2 chemo dose.
The next appointment is 11-13-19, and my dad feels weak and not eating only drinking. Don't know what to do and would like to aks the doctor about Immunotherapy or what should be the next step because dont see improvements in the liver.
Please, if you have any advice or suggestions about next step I will be greatly appreciate it.
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Samdres
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PSA will increase immediately after chemo because cancer cells are dying. Hopefully, it will decrease eventually.
My friend, also with extensive liver mets, is responding well to cabazitaxel + carboplatin. His LDH got very high at first, but has come down now. My friend gets an antihistamine before each infusion, and comes back a couple of days afterwards for 1-2 liters of iv fluids.
If his liver can be biopsied without incurring excessive bleeding, an IHC analysis is probably a good idea; a genomic test requires more tissue, and may sometimes be useful if possible.
Exactly the same, my dad is getting cabazitaxel + carboplatin and yes, he is going for IV fluids and after that he feels better. He already got a biopsy in the liver, what do you want to know ? thanks for your reply
That identifies it as acinar adenocarcinoma of prostatic origin. Was there anything about chromogranin A, synaptophysin, CD 56, INSM1 (these would be rare), or PSMA? Let me know which clinical trials she is considering.
They may not have checked for those. If they have retained the tissue, they can stain for those. I'll PM you.
Dear samdres, I am sorry that your father suffers so . 😫APC is a gut wrenching brutal disease when it’s rolling on us .its bad .. I’m glad the catheter is out and no blood . Not eating is detrimental ...Get him his favorite ice cream ,he needs calories ..Try anything to raise his spirits ... Others with expert advice will answer you what to do . I just applaud you as his advocate .. love him a lot . Comfort and consol him .. Thats what counts . Stay strong yourself in order to be by his side .. God Bless🙏
Been off a month for vacation at Portland Burn Center. Don't recommend needing them. Pain and extreme weakness from burn, grafts and a month in bed. Just when I was finally getting strength back a year and a half after chemo.
This may be the answer to your question. From Shooter1's previous post :
"Must wear gauntlet gloves to put wood in stove otherwise I burn the back of my hands without any feeling, just get blisters. Any Ideas?? Sometimes new normal kind of sucks.
Got out my trusty antique kerosene weedburner, fired it up and during use it split the hose between pressure tank and burner. My right side was sprayed and arm fired up. Fire=fuel, oxygen and heat, No way to get rid of fuel or oxygen with petrol fire, so walked to nearest hose bib and ran arm under it to cool pealing burned cloth and skin off as I got fire out. Thought I had it until I looked over shoulder and saw flames there. Back under water again. Got it all that time. Wives really, hate it when you go into house yelling for help. Dr's tell me months to recover. Stripped thigh and side/flank for graft material. Only one long surgery acct. my sensitivity to general anesthetic . 10% 3rd degree +10%+ skin removal for grafts,my body suffers. Makes prostate surgeries look easy. Doug .
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Is it true that in Adv PC patient life after chemo is just 2 years? Pls advice
I'm new here, but been reading for a while! Really need help from all the knowledgeable people here!
Slowly Rising PSA and Chromogranin-A
What clinic trials have been successful?
Lynparza? Mixed blessing.
