Hi All,
I stumbled upon this recently and thought I would post it as I know many of you guys doing your own research [I feel like some of you guys know more than the Dr's 
] Hope this is helpful.!
sciencedaily.com/releases/2...
A new study from researchers at the University of Michigan Rogel Cancer Center finds that the gene FOXA1 overrides normal biology in three different ways to drive prostate cancer. They refer to the three classes as FAST, FURIOUS, and LOUD to reflect their unique features. The findings are published in Nature.
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FOXA1 was previously known to be mutated in prostate cancer, but its biological functions were poorly understood. Scientists were uncertain if FOXA1 was an oncogene that fueled cancer or a tumor suppressor that hit the brakes. The Rogel Cancer Center team now clarified FOXA1's role as a driver oncogene, in addition to classifying the three novel FOXA1 alterations.
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"Oncogenes tend to be easier to develop therapies for as you could theoretically block them with targeted medicines," Chinnaiyan says. "However, FOXA1 is a challenging target because it is a transcription factor, a class of proteins notoriously difficult to inhibit with small molecules. However, scientists are now developing innovative strategies to go after these 'undruggable' targets."
We might for the first time really be thinking of cures of cancer’
Need an Advise and Info on Very Experienced Doctors and Centers to do Proton Treatment of the Prostate in Oligometastatic Setting
How highs and lows in testosterone levels ‘shock’ prostate cancer cells to death
