The human microbiome and its link in prostate cancer risk and pathogenesis

[dmt1121]

I know that many of you may have probably already read this study but I found the perspective fascinating. It supports the theory that what one eats does matter. Certain diets can cause inflammation and an imbalance of the microbiome in the gut, which may impact risk for developing and/or encouraging growth of PCa. Of course, there are many other variables that influence risk, as mentioned in the study.

The article does suggest that more research is needed in this area to provide a better understanding of the mechanisms at work and if there are treatments that could be developed and employed to provide another tool in the fight.

It should be noted that the study found that chemotherapy reduces the gut macrobiotic diversity. This macrobiotic diversity is generally associated with men with healthy prostates and a lack of macrobiotic diversity is associated with men with prostate cancer. This is not to say chemotherapy is not effective in many cases. However, it may also contribute to an increased risk of developing prostate cancer growth and its spread.

ncbi.nlm.nih.gov/pmc/articl...

[Nusch]

I trust that there is a relationship, not only with prostate cancer but other diseases and immune system as well. Since I’m on WFPBD (whole food plant based diet) my body changed to the better in many aspects, feeling much better overall and stay free of influence, cold and other infection diseases.

[dmt1121 in reply to Nusch]

I believe so but have no information on its broader applications.

[Grandpa4]

I think the problem in this area is that we know it is important in a variety of diseases but the important differences may vary depending on your genetic and the disease being studied. Therefore, we have no idea what to tell individual patients.

[dmt1121 in reply to Grandpa4]

Very true.

[turkeyjoe1]

Best thing you can do for your gut health is add fermented sauerkraunt or kimchi. It's in the refrigerator section at your store. Do not heat it.

[j-o-h-n in reply to turkeyjoe1]

In a roll ........... It's called old enemy/new enemy sandwich...........

Good Luck, Good Health and Good Humor.

j-o-h-n Tuesday 02/28/2023 3:28 PM EST

[dmt1121 in reply to turkeyjoe1]

Do you have any studies you can share on this?

[Darryl Partner]

Dr Espinoza discusses microbiome in this video Best Prostate Cancer Diet and Lifestyle

youtu.be/J2DryV9E914(Not working as expected?)

[Nusch in reply to Darryl]

Thx Darryl! I watched the video and need to add a couple of things:

1. Salmon: While stating that non-organic spinach should be avoided, he is not mentioning, that most salmon today come from fish farms. They live a short life of full of stress, the stress hormones are stored in the muscles and meat. They get vaccinated to get the red color and they are full with antibiotics. Their food is junk food. So you can imagine, how healthy this can be.

2. Chicken: Same is true for chicken, sometimes even worse. Chicken „live“ in mass of 30-50/m2. Antibiotics, junk food, rapid weight gain, stress for their whole life. Healthy?

3. Oil: What he says about fruit juice I would also apply to oils: An oil is only a very concentrated form of a fruit, missing major parts of the whole food, e.g. olives compared to olive oil. So I avoid it. For coconut oil, there are many studies that this is the worst oil of all. Same for palm oil.

[Mike2023]

Other than foods, including various fermented products, any probiotic that would counter the "odd" composition of PCa patients? IMO, the study just further supports arguments for older / ill patients to seek FMT (Fecal microbiota transplantation.) I am still looking for good sources.