" 31.9% were bio-chemically Disease Free (bDFS) at 15 mo. ! ! ! ! !
All patients with Bio-chemical Failure (BF) (n=43 - out of 57) underwent a repeat PSMA-PET scan, which revealed no in-field failures. ! ! ! ! !
Median bDFS was not affected by prostate-specific antigen (PSA) at diagnosis, Gleason score, time from diagnosis to SBRT, site (bone vs LN), PSA doubling time before SBRT, or number of metastases. ! ! ! ! !
Failures were somewhat less common in patients with low PSA before SBRT. Toxicity was rare: no patients developed grade ≥2 late toxicity."
Bottom line for me is: --
(A) even after metastasis occurred -- apparently one third were cured with SBRT alone (no ADT to skew the results) and
(B) all of the remaining two thirds were cured in the treated areas, and
(C) SBRT ends it in that area -- unlike ADT alone that does not cure anyone and causes cancer to become drug resistant 80% of the time.
(D) even though it reoccurred in other areas it could be treated there with SBRT as well.