Does this mean we should supplement Taurine; I take it at night to help me sleep

[900312611]

From PubMed.gov

Taurine Attenuates Epithelial-Mesenchymal Transition-Related Genes in Human Prostate Cancer Cells.

Tang Y1,2, Kim YS3, Choi EJ4, Hwang YJ5, Yun YS1, Bae SM6, Park PJ2,3, Kim EK7,8.

Author information

Abstract

Prostate cancer is the most common non-cutaneous cancers among men and the second leading cause of cancer-related deaths among men. Aberrant activation of the epithelial to mesenchymal transition (EMT) has been exhibited to be one of the most common causes of treatment failure and death in cancer patients. In cancer cells with metastatic competence, the E-cadherin switch is a well-established hallmark. Suppression of E-cadherin through its transcriptional repressor SNAIL is thus a determining factor for EMT. TWIST1 is an important transcription factor in EMT, which is present under both physiologic (embryogenesis) and pathologic (metastasis) conditions, and enhances the invasiveness and migration ability of cells. In this study, we investigated the inhibitory effects of taurine on EMT-related genes, such as E-cadherin, N-cadherin, TWIST1, ZEB1, SNAIL, and vimentin. EMT markers were detected by RT-PCR and western blotting. The results showed that taurine down-regulated the expression of N-cadherin, TWIST1, ZEB1, SNAIL, and vimentin. In contrast, taurine increased E-cadherin expression. Our findings indicate that taurine has EMT inhibitory effects on human prostate cancer cells.

[pjoshea13]

It wouldn't hurt.

Here's the link:

ncbi.nlm.nih.gov/pubmed/?te...

Taurine (with or without arginine) may be useful for A-fib.

Improving blood flow may forestall the appearance of HIF-1alpha (hypoxia-inducible factor-1alpha).

-Patrick

[tango65 in reply to pjoshea13]

What is the dose for AF?

[pjoshea13 in reply to tango65]

My wife was taking 2,000 mg taurine (+1,000 mg arginine) just before bed & again on waking up. (On an empty stomach.)

She had been told that she would need a drug for the rest of her life.

After a while, she only needed the amino acids occassionally. She threw the drug away.

Seems that taurine levels are much lower in older people. She takes taurine now & then.

-Patrick

[tango65 in reply to pjoshea13]

Thanks. I really appreciate your reply.

[tango65]

Thanks Nala, I really appreciate your input.

[j-o-h-n]

I can't understand not falling asleep on Sichel Street, L.A.

Best way for me to fall asleep is to close my eyes...

Good Luck, Good Health and Good Humor.

j-o-h-n Thursday 05/30/2019 8:03 PM DST

[Hidden]

Yes, I also take Arginine and Taurine for a-fib. I remain on meds for a-fib too. I guess it's a nice bonus that Taurine can help fight prostate cancer. Have there been double blind randomized trials to prove this efficacy? Just kidding. I like supplements.

[GeorgeGlass]

Nalakrats, So it's better to take the Taurine at night before bed, rather than in the daytime? Just once at night? It wouldn't conflict with melatonin would it?

George