What does this mean ? Scared to death - Advanced Prostate...

Advanced Prostate Cancer

21,428 members26,837 posts

What does this mean ? Scared to death

Chris52981 profile image
39 Replies

While there is limited distension of the urinary bladder, there is thickening and irregular stranding involving the anterior urinary bladder wall. Additionally, focal intense fluciclovine uptake is noted within the wall. This was not appreciated on the August 6, 2020 PET-CT scan.

This was from Axumin scan

Written by
Chris52981 profile image
Chris52981
To view profiles and participate in discussions please or .
39 Replies
tango65 profile image
tango65

What was the interpretation of the radiologists reading the PET/CT? If there is intense (SUV?) accumulation of the tracer in the bladder wall it could indicate an extension of the cancer into the bladder. False positives have been described with the Axumin scan.

Chris52981 profile image
Chris52981 in reply to tango65

IMPRESSION

1. Suspicious, new, fluciclovine uptake in the gravity independent, anterior urinary bladder wall. Urinary bladder evaluation is recommended.

2. Persistent lytic focus a mildly increased radiotracer activity in the right lateral 3rd rib, suspicious for osseous metastatic disease. Greatly improved, fluciclovine uptake in the left iliac crest, likely representing successfully treated metastasis.

3. No new suspicious radiotracer uptake in the prostate or axial/appendicular skeleton.

4. Multiple sclerotic foci without significant metabolic activity, likely representing treated disease.

tango65 profile image
tango65 in reply to Chris52981

The radiologists did not make the call the finding is an extension of the cancer. They want an evaluation by the urologist. The urologist will do a cystoscopy and possibly a biopsy to determine what is going on. Fluciclovine is not an specific PC tracer. It could be uptaked by other tissues.

ajronline.org/doi/10.2214/A...

Chris52981 profile image
Chris52981 in reply to tango65

Ok does it detect bladder cancer though

Chris52981 profile image
Chris52981 in reply to Chris52981

Like no prostate bladder cancer

tango65 profile image
tango65 in reply to Chris52981

Yes, it could.

journals.lww.com/nuclearmed...

Chris52981 profile image
Chris52981 in reply to tango65

I just don’t uNdetsyand if the Zytiga and lupron is working cause it seems in bones and now that but I have read in other reports that he has mild diffuse thinking like 5 years ago on MRI

Chris52981 profile image
Chris52981

Oh ges this is so scary I’mFreaking out

tango65 profile image
tango65 in reply to Chris52981

Benign conditions could also uptake fluciclovine. The bladder examination will resolve this situation. It could be a post radiation cystitis.

"Several benign conditions can demonstrate increased 18F-fluciclovine uptake, leading to false-positive findings (48). Benign prostatic hypertrophy, acute and chronic inflammation (including postradiation inflammation), and infection all demonstrate varying levels of 18F-fluciclovine uptake. Reactive lymph nodes with uptake have been described adjacent to vascular grafts. Cutaneous and musculoskeletal inflammation has variable activity."

ncbi.nlm.nih.gov/pmc/articl...

Chris52981 profile image
Chris52981 in reply to tango65

Even if it would be prostate cancer there is that still treatable - Zytiga and lupron is first tx since biochemicalReoccurrence and psa . 19

tango65 profile image
tango65 in reply to Chris52981

For what my opinion is worth, with stable PSA and not major PC radiographic changes, an extension of the PC into the bladder seems unlikely. Late radiation cystitis may develop years after the radiation treatment.

Chris52981 profile image
Chris52981 in reply to tango65

Ok hopefully that is what it is - he always had the diffuse wall thinking even in 2015 MRI of pelvis when he started his radiation-

tango65 profile image
tango65 in reply to Chris52981

Lab tests and scans always generate a lot of anxiety. I wish you the best of luck.

Chris52981 profile image
Chris52981 in reply to tango65

Thank you so much for ur help I feel better - I just pray everything is ok- it’s just so scary when they release results and you don’t have anyone working on the weekend to help relieve anxiety

Chris52981 profile image
Chris52981 in reply to tango65

So if something like that would be prostate extension is it possible that he would stillBe able to be treated and also would they just change meds

tango65 profile image
tango65 in reply to Chris52981

Wait until the urologist sees him. Nobody knows if this is PC or any other kind of cancer.

Chris52981 profile image
Chris52981 in reply to tango65

He will see his MO who specializes in prostate

Chris, quit worrying yourself to death about your dad. You don’t know and neither does anyone in this group. It’s what happens when one gets an early report. Do what is recommended. Have your dad see his Uroligist with the report. Have your dad’s Medical Oncologist go over the report. Have your dad’s Radiation Oncologist go over the report. His team are pros, you are not.

Case in point, I once had a doctor worry me to death about a scan. When I got to the right doctor and he reviewed and ran a test, he had the answer. I asked what he found, his reply was a piece of shit.

Good luck

GD

maley2711 profile image
maley2711 in reply to

needed the laugh!!

ppulatie profile image
ppulatie

I had the same on one CT Scan two plus years ago. Was cancer on the bladder inner wall. Doc did a TURP and removed the inner wall cancer and been good to go since then.

Chris52981 profile image
Chris52981 in reply to ppulatie

Was it prostate cancer or bladder cancer

ppulatie profile image
ppulatie in reply to Chris52981

Stage 4 Prostate Cancer. Had spread to illium, sacrium (sp) and one spot on L11 plus the upper bladder wall.

2 years almost now on Xtandi and Lupron. 5 years total. PSA down to .21 as of two weeks ago. High was 80.08 in Oct 2016.

Chris52981 profile image
Chris52981 in reply to ppulatie

Did u have to get a cystoscope fromUrology to check it out

ppulatie profile image
ppulatie in reply to Chris52981

Have had 3 cystoscopies total. Plus 2 MRI's, 3 CT scans and 3 ultrasounds, plus 1 bons scan. Have a great team of docs all working together to keep me going. And that is the key, a great team of docs.

Chris52981 profile image
Chris52981 in reply to ppulatie

So his pet scan showed uptake on bladder so his MO sent himTo urology is that common to do or would they just handle it

ppulatie profile image
ppulatie in reply to Chris52981

Generally one would expect the Urologist to get involved. They specialize in bladder, etc. so they would do the cystoscopy and see what was happening, plus check out the prostate, etc.

Chris52981 profile image
Chris52981 in reply to ppulatie

So even if it was prostate cancer to the bladder that would involve urology

ppulatie profile image
ppulatie in reply to Chris52981

Yes

Chris52981 profile image
Chris52981 in reply to ppulatie

I’mSorry I am

So

Confused- so when they thought urs metastasised to

The bladder the medicinal oncologist didn’t handle that they sent u for cystoscope to verify from

Ur urologist

ppulatie profile image
ppulatie in reply to Chris52981

In my case, the urologist found it first. He did a cystoscopy for a bladder stone the size of a golf ball. Caught it then. Then went in and lasered the stone, and TURPed the prostate.

My MO would not do that type of procedure. She watches the cancer overall and prescribes the medications as needed. But she listens to me and the Urologist and acts as needed.

Other MO's might do a cystoscopy IF they specialize in prostate cancer, but would believe that most would refer back to the urologist otherwise.

Chris52981 profile image
Chris52981 in reply to ppulatie

Yes and I don’t think our MO thinks it’s prostate cancer Bc everything was going in the right direction and clearing up! I just hope it is not a primary bladder cancer.

Chris52981 profile image
Chris52981 in reply to ppulatie

What did they do on ur bladder to get rid of it

ppulatie profile image
ppulatie in reply to Chris52981

Went in with a "knife" and cut it out of bladder wall. Warning....do not look up device used to cut it out. It scares the hell out of you, knowing that it is being put up your peepee hole.

j-o-h-n profile image
j-o-h-n

We all are scared to death.....It's worse when we're scared "to shit"....

Good Luck, Good Health and Good Humor.

j-o-h-n Sunday 08/29/2021 12:11 PM DST

Seebs9 profile image
Seebs9 in reply to j-o-h-n

Great to see your wise-ass posts again, you are the best!

j-o-h-n profile image
j-o-h-n in reply to Seebs9

Thank you sir.........Now if women would only call me the beast.... oops best......

Good Luck, Good Health and Good Humor.

j-o-h-n Sunday 08/29/2021 6:12 PM DST

in reply to j-o-h-n

The best or the beast , either way you get respect!😂

in reply to j-o-h-n

The beast from the East.

j-o-h-n profile image
j-o-h-n in reply to

and a Peddie with a machete...

Good Luck, Good Health and Good Humor.

j-o-h-n Monday 08/30/2021 9:59 PM DST

You may also like...

Spike in RBC. What does it mean?

Extensive spine Mets. I started ADT within days and chemo within a week. Did 10 rounds and ended...

What is this and what does it mean….

Haven’t posted in a while been really really sick…went to get a cystoscope and it was unbearable!!….

Positive Guardant 360 Test-What does it mean

month “vacation” from Lupron/Zytega. With my PSA rising again, my most recent PSMA scan revealed a...

What does it mean

Scan came back and husband has enlarged retroperitionel lymph nodes prostate carcinoma Osseous...

It’s back and I’m scared to death!

The VA oncologist wants to wait until August 4th to get a CAT scan and biopsy before he starts...