Dad 60 years young, Advance stage, Multiple Mets, Had first round of chemotherapy. Need help and guidance on what to expect.

[Shahbazahmedazmi]

Dear All,

Thank you for your support and guidance.

My Dad is 60 years young with 59.6 kg body weight. He is based in India and currently getting his treatment in Medanta The Medcity hospital in Gurugram (Near New Delhi). I forgot to mention that he is diabetic as well. Diabetes was also diagnosed at the same time as APC. Does this changes anything?

One and a half month ago, Dad was diagnosed in advance prostate cancer with Gleason score 9 (4+5) and with multiple Mets in multiple bones.

4 weeks ago he went through orchiectomy and last week he went through his first chemotherapy therapy. Doctors are giving him Docetaxal + wysone, Zoledronic acid and biclutamide.

After chemotherapy he is having moderate to severe pain in calf muscle, severe weakness and semi-solid to liquid rounds in the toilet. Is this normal? Is this is how he is going to react after every chemotherapy? What can we expect after every chemotherapy? The plan is for 6 cycles of chemotherapy.

Also, One of the doctors gave him Ultracet for his pain which is sort of opioid. That medicine is making me uneasy. Shall we stop Ultracet?

Kindly do let me know with your comments what to expect so that we can make decisions based on knowledge and not on emotions.

Thanks and Regards

Shahbaz Azmi

[tango65]

Fatigue, weakness, diarrhea and myalgia are undesirable effects of chemo.

rxlist.com/taxotere-drug.htm

If he is in pain he should be treated with medicines which could reduce the pain. Ultracet (tramadol) is used in this situation. This link has some information about tramadol:

rxlist.com/consumer_tramado...

[Shahbazahmedazmi in reply to tango65]

Thank you Tango65 for your quick response

[Shahbazahmedazmi in reply to tango65]

I forgot to mention that he is diabetic as well. Diabetes was also diagnosed at the same time as APC. Does this changes anything?

[tango65 in reply to Shahbazahmedazmi]

What is the treatment for the diabetes? Are they given him prednisone with the chemo?

[Shahbazahmedazmi in reply to tango65]

At the moment I am giving him insulin shots before every meal. They did gave him some steroids before chemo. I do not know if it was prednisone or something usual.

[tango65 in reply to Shahbazahmedazmi]

They need to monitor him closely during this treatment and adjust medications if needed.

[Tall_Allen]

Those are very typical symptoms. His QOL is likely to be better for having gone through the 6 infusions.

[Shahbazahmedazmi in reply to Tall_Allen]

Hi Tall_Allen, Thank you for your quick response. Last week was his first chemotherapy..5 more are still to go..

[Shahbazahmedazmi in reply to Tall_Allen]

I forgot to mention that he is diabetic as well. Diabetes was also diagnosed at the same time as APC. Does this changes anything?

[Tall_Allen in reply to Shahbazahmedazmi]

Some believe that metformin may slow progression.

[Shahbazahmedazmi]

I forgot to mention that he is diabetic as well. Diabetes was also diagnosed at the same time as APC. Does this changes anything?

[Ankitsharma021290]

Hi Shahbaz...my father too in almost same condition...the treatment is going on in AIIMS new delhi...but they did not advise any surgery and all...just gave a radition where pain was most and due to which he is not able to walk....now he can stand up slowly ....and first they gave firmagon(degarlix), Zoledronic acid and biclutamide Docetaxal...and than PSA level down from 168 to 38 and now they changed after one month...they started.....firmagon(degarlix) with zytiga wypone....But no chemo was suggested till now...as biospy report is not in hand till now...

[Cheerr]

Hi,

How is your dad doing now?

Wishing him the best in the upcoming treatments.