Erleuda + Lupron + Xgeva

[MJCA]

Hello Gents,

Thought I would share my experience on these meds.

Briefly: Age 59, Gleason 7, Stage IV, diagnosed 2005, not encapsulated

Treatment: Lupron 2 years, brachytherapy, 36 radiation

As PSA would increase back on Lupron for a year.

While on Casodex/Lupron PSA continued to rise. No mets. PSA almost quintupled to 13.4 in 6 months.

Started this holy trinity on my birthday, 18 January. After 2.5 weeks my PSA was 4.4. After 6 weeks, my PSA is now 2.8! Freakin amazing.

Side effects:

Lupron (I believe this is my 5th round): depression, fatigue, hot flashes and then I get cold.

Erleada/apalutamide: fatigue, it has decreased my need to urinate as much!

Xgeva: joint pain, nausea, headaches

Compared to the results, the side effects are a small price to pay.

Good health.

Mark

[Crabcrushe]

Get some venlafaxine, bro. Night & day...

Crabcrusher

[MJCA in reply to Crabcrushe]

LOL. I’m already on 2 meds. Besides the cancer there’s just a lot of other shit going on in my life. Thanks. I am speaking to someone weekly as well. I am finally attending a monthly support group.

[Crabcrushe in reply to MJCA]

Ok, but soon after I started, the severity of the hot flashes went away.

Crabcrusher .

[MJCA in reply to Crabcrushe]

Mine aren’t that bad this time around.

[larry_dammit]

Congrats. No Mets sounds good to me. Know about the monster and lupron and Xgeva. Monthly shots for me plus Xtandi. 30 months and counting.

[MJCA in reply to larry_dammit]

What is your status?

[larry_dammit in reply to MJCA]

Well. Stabil I guess. Doctor is happy and says I am doing good. I feel pretty good except for rib pain which comes on when I try to lift to much. 5 gallons of Gas 😡😡. Not used to havin* restrictions on what I can do. Doctor says I will never be in remission as the cancer won’t go away. Is that what you were asking 😀

[MJCA in reply to larry_dammit]

Dammit Larry - no. 😉 Yes, part of it. Where do you live? How old are you?

[larry_dammit in reply to MJCA]

Sorry. Diagnosed at 66 yrs old, just before my birthday, I live in northwest Missouri. I doctor at Mosaic hospital in St.Joe. Missouri once a month since I started this. Have Mets in my ribs, spine and lymph nodes. Last scan was in Dec. hot spots are not getting any bigger, just no smaller 😡

[MJCA in reply to larry_dammit]

Thanks. And never a need to apologise; we're all on meds!

Sounds to me like your doc is very straightforward. I like that. I am so sorry to hear about your Mets. I am really glad you don't have much pain.

Just remember we're here for you!

[monte1111]

If I did my math right (damned lupron) you've been doing this about 14 years. Way to go Mark. Keep on kicking it!

[MJCA in reply to monte1111]

Thanks. It was difficult to accept at age 45. My PCa has been mainly under control, but now it has changed and I am staying informed and active again!

[ROLNCIN1]

Hello Mark,

This is wonderful that these 3 drugs are working for you.

My husband may be heading in this direction as his PSA is slowly creeping up.

He has been on continues Lupron for 7 years without a break and Xgeva for 5 years.

Keep us posted that you are still on right track. Think positive.

BOOGEE

[Josianaperez]

Hello, you give me a lot of hope, my partner is 47 and was detected last year in stage IV, gleason 8, with bone metastases. It takes a year of treatment, started with chemo (docetaxel), radiation and now hormonal blockade. greetings to all.

[gabz47 in reply to Josianaperez]

how's your partner doing? i just got diagnosed with stage 4, gleasom 8, with bone metastases. scary times for me.