New member

[Unusualmint45]

I had a RP in Jan 2018. Gleason 9. PSA prior to surgery was 1.75. Met to lung only. Was started on docetaxel/ casodex/ lupron. Had a disected carotid artery. Had to be treated with blood thinners for 3 mo. OD decided to change to zytiga and prednisone/ along w lupron. PSA have been running <0.02 for last 9mo. Trying to follow plant based diet.

[Tall_Allen]

Did the chemo shrink your lung met? Any blood work to detect levels of chromogranin A, synaptophysin or neuronal-specific enolase?

[Unusualmint45 in reply to Tall_Allen]

Yes Cscan showed no new nodules and prev nodules decreased in size by greater 50%. Do not know the other tests you mentioned.

Thanks

[Tall_Allen in reply to Unusualmint45]

You can ask your oncologist for them, but if docetaxel was effective, the blood tests probably won't tell you much.

[Unusualmint45 in reply to Tall_Allen]

I only had one docetaxel treatment and then stopped because of dissected carotid. OD felt chemo would interfere with carotid healing.

Therefore changed me to zytiga.

[Unusualmint45 in reply to Tall_Allen]

Sorry i haven't replied sooner, but found out that

chromogranin A, synaptophysin , were neg - pos for pancytokeratin Like I mentioned before I only had one treatment w docetaxel because of my disected carotid and has been resolved. I've been on abiraterone/prednisone +lupron

[MichaelDD]

I'm the same. Metastasis to lungs only. Did GA68-PSMA scan last October at UCSF. Started Zytiga Lupron Prednisone Dec 1st. First CT scans next week. Also blood work. PSA dropped to .013 from 1.99 .

[Unusualmint45 in reply to MichaelDD]

Hi MichaelDD

I have been on zytiga/lupron(every 3mo.) for 8mo. My PSA has been

<0.02. I get blood drawn every mo. The waiting for test results is hard. Hope all goes well. A prayer helps me. Stay positive

[MichaelDD in reply to Unusualmint45]

Thank you. See my Radiologist every 3 months. Saw him yesterday for the first time since the scan found the metastasis. He walked in and said "you're pretty rare'. I will be following you to see your journey.. not many lungs exclusive. I too see my MO every month at least. Blood drawn monthly too. Only way to track nodules is scans and psa. Best to you..

Michael.

[Unusualmint45 in reply to MichaelDD]

Hi Michael keep me updated on your progress. Hope you're doing well at this time . I'm interested in what your Dr. suggests, if anything at this point, other the the treatment regimen we're on now.

[Unusualmint45 in reply to MichaelDD]

Hi Michael --my 1/18/19 CT scan was compared to 2/21/18.

Findings:

Neck base No lymphadenopathy

Mediastinum and lymph nodes- No lymphadenopathy

Lungs: Significant interval decrease in size of multiple bilateral

pulmonary nodules. For example, a peripheral nodule in left lower lobe currently measures 3mm and previously measured 7mm. No new nodules.

Upper abdomen: unremarkable

Soft tissue/musculoskeletal: no acute osseous abnormality

Impression- Significant interval decrease in size of multiple bilateral

Nodules, consistent with interval treatment response. No new nodules.

I'm having no side effects from lupron and zytiga to speak of.

Losing muscle and some weight so trying to increasing calories and weight has stabilized. Working out 3+ times a week running 2-3 miles. Weight training to keep what muscle I have.

Hope you are doing well. Keep in touch.

Frank

[j-o-h-n in reply to Unusualmint45]

waiting sucks... Pca sucks sucks....

Good Luck, Good Health and Good Humor.

j-o-h-n Friday 02/08/2019 5:41 PM EST