I belatedly learned from his family today that Herb left our world in March 2018 as a result of his advanced prostate cancer. Herb ( herb_8789 ) did not post/reply here extensively, but he was always generous with me in Chats and personal emails we exchanged in 2017, and he followed this forum closely. Herb died in his later 80s, after a relatively short decline after both Zytiga and Xtandi could not keep ahead of his advancing disease. He was a positive advocate for the benefits of palliative care, started earlier rather than later. Fortunately, Herb died and his wife relocated many months before the massive wildfire destroyed their former home along with thousands of others in the town of Paradise, California in recent months. My continued condolences to his family, who celebrated his life in Paradise, California in April 2018, well before the time of the big fire.