Do any of these help? : In addition to... - Advanced Prostate...

Advanced Prostate Cancer

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Do any of these help?

GolferDan profile image
24 Replies

In addition to treatments anyone have any luck with any of the following foods or supplements?

AHCC

Cayenne Pepper

Tumeric/Curcumin

Ginger

B17

Pomegranate

Baking soda

Or any others I don’t know about??

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GolferDan profile image
GolferDan
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24 Replies
pjoshea13 profile image
pjoshea13

See my old posts:

"Foods/Supplements-Vitamins: Capsaicin - Cayenne"

"Foods/Supplements-Vitamins: Curcumin"

"Pomegranate"

Search on "Foods/Supplements-Vitamins:" to find similar posts.

The following items do not pass the smell test IMO:

... B17 (not a vitamin)

... baking soda

-Patrick

in reply topjoshea13

Who’s test?

Chat me up !

Pjoshea13 has it down ..

Tall_Allen profile image
Tall_Allen

The only supplement I know of that has been proven in a randomized clinical trial is sulforaphane.

cancerpreventionresearch.aa...

The only one on your list that has been disproven in a randomized clinical trial is pomegranate juice extract:

nature.com/articles/pcan201532

I would avoid B17 based on this:

ncbi.nlm.nih.gov/pubmed/161...

Watch the sodium you are taking in with baking soda, and be careful of alkalosis. Otherwise I don't think any of the others will harm you, although the benefits are highly uncertain.

VisualDeadlock profile image
VisualDeadlock in reply toTall_Allen

Thank you Tall Allen! Adding Broccomax to my list as well. Any idea on dosage (1 - 3 tabs daily - the Jarrow Max w/Myrosinase product)?

Tall_Allen profile image
Tall_Allen in reply toVisualDeadlock

As you see in that French RCT, they gave everyone 60 mg/day.

AnnieAppleseed profile image
AnnieAppleseed in reply toTall_Allen

Because natural substances cannot be patented, there will never be multi-centered randomized trials. But many small studies have been done over many years. I created my nonprofit Annie Appleseed Project to shate the evidence. BTW, no clinical trial of Laetrile, aka vit B17 has ever been done. You can look up the book, movie and statements made by Ralph Moss, PhD about his experiences at MSKCC AND the research done there in the 1960's. I know him personally since 1995, he is a man of integrity.

Tall_Allen profile image
Tall_Allen in reply toAnnieAppleseed

Annie - we have seen time and again that the small studies you refer to are only useful for hypothesis generation, but usually get reversed when tested against a double-blinded placebo. This really hit home with the NIH-sponsored SELECT randomized clinical trial (RCT) of Vitamin E and Selenium. Although Vitamin E was ASSOCIATED with better outcomes in the kinds of studies you find convincing, The RCT PROVED that vitamin E (of the kind and doses many men were buying in health food stores) actually CAUSED prostate cancer to get worse. This led to many questions about the use of anti-oxidants and how they can make our cancer worse by interfering with our body's natural cancer-fighting mechanisms.

Most recently, some RCTs (they actually do occur!) have reversed what we thought we knew about several substances from the kinds of smaller studies you put your faith in. Based on those, we can comfortably cross off our list omega-3 fatty acid pills, green tea extract, lycopene, and pomegranate juice extract.

One use of the kinds of smaller studies you rely on is to eliminate substances that demonstrate even the slightest hint of harm. That list includes high doses of Vitamin D, calcium, "Vitamin B-17," and folates.

AnnieAppleseed profile image
AnnieAppleseed in reply toTall_Allen

There are such separate worlds. The P1 trial was announced at a meeting. I immediately suggested that the dose was wrong, the type of vit E, the wrong selenium, and the multi offered, since vit E needs vit C to fully function, were all wrong. The multi, all synthetic and artificial ( I know because the Canadian supplier faxed me a list of ingredients), could never do a good enough job.

There's a whole separate world of researchers and practitioners who are aware of the better types and dosages. I hate that it is so separate.

No vitamin is truly of value to our human bodies when used alone. No single item works properly because we need combinations of nutrients.

Tall_Allen profile image
Tall_Allen in reply toAnnieAppleseed

If you are talking about the SELECT trial, they used the kind and dose of Vitamin E that is most commonly purchased. it was as "real world" as it gets. It was one of the best trials ever done. There were indeed combination effects but in the adverse direction - supplementing selenium in men who already had adequate levels made them worse. Vitamin E supplementation in men with low selenium made them worse.

ncbi.nlm.nih.gov/pmc/articl...

Our bodies evolved to sort out the nutrients and micronutrients it needs to function well from the foods we eat. Those who try to 'outsmart' our bodies by overloading it with micronutrients at dosages that would never appear in our foods may do harm in their ignorance.

in reply toTall_Allen

I love them all..

FCoffey profile image
FCoffey

Tumeric/Curcurmin has anti inflammatory effects.

Cancer Center UK has a page on tumeric

cancerresearchuk.org/about-...

"A phase I clinical trial looked at giving curcumin to 25 patients with precancerous changes in different organs. This study seemed to show that curcumin could stop the precancerous changes becoming cancer.

"Research has also shown that there are low rates of certain types of cancer in countries where people eat curcumin at levels of about 100mg to 200mg a day over long periods of time.

"But currently there is no conclusive research evidence to show that turmeric or curcumin can prevent or treat cancer.

Cancer treatment and turmeric

"A number of laboratory studies on cancer cells have shown that curcumin does have anticancer effects. It seems to be able to kill cancer cells and prevent more from growing. It has the best effects on breast cancer, bowel cancer, stomach cancer and skin cancer cells.

"A 2013 international laboratory study looked at the effects of a combined treatment with curcumin and chemotherapy on bowel cancer cells. The researchers concluded that the combined treatment might be better than chemotherapy alone.

"A 2007 American study in mice seemed to show that curcumin helped to stop the spread of breast cancer cells to other parts of the body."

In January there was a lot of news about a woman who claims to have cured her cancer with Turmeric. Not a study, but her doctors were impressed. She had stopped conventional treatment.

dailymail.co.uk/health/arti...

"Her doctors, from Barts Health NHS Trust in London, wrote in the British Medical Journal Case Reports: ‘To the best of our knowledge, this is the first report in which curcumin has demonstrated an objective response in progressive disease in the absence of conventional treatment.’

"The experts, led by Dr Abbas Zaidi, said some myeloma patients took dietary supplements alongside conventional treatment but ‘few, if any, use dietary supplementation as an alternative to standard antimyeloma therapy’.

"But they added: ‘In the absence of further antimyeloma treatment the patient plateaued and has remained stable for the past five years with good quality of life.’"

VisualDeadlock profile image
VisualDeadlock in reply toFCoffey

I just wanted to add a cautionary note about Curcumin. Based on what I have read, it tends to contract the gallbladder somewhat. If you suffer from gallstones, you may want to avoid Curcumin. With that being said, I have gallstones, and decided to take Curcumin anyways. I haven't noticed pain in that area, but I've also only been on it a little while.

AnnieAppleseed profile image
AnnieAppleseed in reply toFCoffey

There are many small studues of curvumin and turmeric. Because natural substances cannot be patented, there may never be Level I trials, but lots of evidence.

Tall_Allen profile image
Tall_Allen in reply toAnnieAppleseed

There has certainly been a LOT of studies on it, yet efficacy has never been proven. The authors of the following meta-analysis published in ACS' Journal of Medicinal Chemistry write:

"Curcumin, on the other hand, is more like a missile that has shown excellent promise in early testing (in vitro), even though this testing may have been bedeviled by design problems that led to several misfires. The structure of [curcumin] suggests that it might be unstable in a biological setting, and in fact, it is: both its in vitro and in vivo stabilities are abysmal (T1/2 < 5 min; F < 1%) [the half-life in the blood is under 5 minutes] relative to commercial drugs."

"To our knowledge, [curcumin] has never been shown to be conclusively effective in a randomized, placebo-controlled clinical trial for any indication. Curcumin is best typified, therefore, as a missile that continually blows up on the launch pad, never reaching the atmosphere or its intended target(s). These results have given curcumin the label of pharmacodynamically fierce (hits many targets) yet pharmacokinetically feeble (does not get to its targets). While these failures would normally end further research on its use as a therapeutic, they apparently have not deterred researchers interested in its development. Accordingly, major resources have been expended on research enterprises that involve curcumin as a key study agent. From 1995 to the present, according to the NIH RePORTER database (query of the term “curcumin” in keywords, titles, and abstracts), federal funds exceeding $150 million have been awarded for projects that are linked, directly or indirectly, to the biomedical exploration of curcumin. This result gives an approximate estimate of the order of magnitude of resources (not scientific significance) that are used directly or indirectly for experiments with curcumin and its analogues."

pubs.acs.org/doi/10.1021/ac...

While technical, this analysis should be read by anyone who wants to understand the significance of all the "small studies" that are done, and why they can lead us astray.

FCoffey profile image
FCoffey

This recently published paper found that oral baking soda stimulated a previously unknown nerve center in the spleen that regulates immune response and inflammation.

jimmunol.org/content/early/...

There is a lay language discussion of the research at

lewrockwell.com/2018/04/bil...

I always check Bill Sardi's claims and references; sometimes he goes a bit too far. But he's a good resource for new and information that can be hard to find.

FCoffey profile image
FCoffey

"Or any others I don’t know about?? "

Speaking strictly for me, the list of things I don't know is very, very long. There are a huge number of supplements out there.

Princeps profile image
Princeps

I have used Turmeric pills for knee joint pain; i had difficulty getting up my own stairs to go to bed at nite.

Over the counter capsules; 2 a day. In 2 weeks the pain was gone

in reply toPrinceps

I’ve taken 2 one gram caps with food twice daily of Thorne Meriva 500-sf Curcumin Photosome every day for 3yrs. I also ear fresh organic turmeric, ginger, every day.. Meriva prescribed by natural path with several other daily nutrients. As long as I can afford these nutrients I have no plan to stop there use... Good luck..

VisualDeadlock profile image
VisualDeadlock

GolferDan - may want to look into 5-Loxin or 5-Lox inhibitor as well. Can search this site for posts about it, some folks definitely have it in their regimen, and I will be adding it too.

FCoffey profile image
FCoffey

The dose is pretty small, just 1/2 teaspoon in a glass of water per day. The "baking soda cure" and increasing the body's alkalinity have long been stables of alternative cancer lore. Instances of people who hurt themselves are pretty rare, and tend to involve taking massive amounts. That can shift blood or tissue pH (acidity/alkalinity) which is dangerous.

The small amount of baking soda triggers the spleen to modulate the immune system. It doesn't come close to the amount required to shift blood pH.

People take baking soda for indigestion, for brushing teeth, and many other reasons. I've never read about any problems with these uses.

If something bothers you then stop doing it. I wouldn't expect many folks to react to such small amounts of baking soda, but everyone is different.

SsgCulldelight profile image
SsgCulldelight

natural herbs all always better and yes they help. TheFDA derives all pharmaceuticals from natural herbs, they just water it down.

I do them all GolferDan ..These are all great nutrients. Prescribed by My Nat. Onocologist..

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