High-fat Diets May Promote Prostate Cancer Metastasis, Mouse Study Suggests
January 22, 2018 Patricia Inacio, PhDby Patricia Inacio, PhD
"Loss of two tumor suppressor genes – PTEN and PML – in prostate cancer appears to trigger the progression of disease by turning the cells into fat-producing factories, new research shows. These findings reveal the genetic link between aggressive types of prostate cancer and dietary habits and suggest new therapies for halting disease progression...."
“It was as though we’d found the tumors’ lipogenic, or fat production, switch,” Pandolfi said. “The implication is, if there’s a switch, maybe there’s a drug with which we can block this switch and maybe we can prevent metastasis or even cure metastatic prostate cancer.”