interesting, and encouraging:
"Possibilities for Cancer Therapy
Methyl groups, enzymes, and other DNA accessories, collectively known as epigenetic markers, keep cells on the straight and narrow path, ensuring they divide in an orderly manner and remain true to their nature – that a lung cell, for example, doesn’t suddenly become a kidney cell. One of the most striking features of cancer cells is that the patterns of these markers are altered. This can allow cancer-related genes to become overactive, and disable genes that normally keep cell growth in check.
As scientists map ever more of the epigenetic disruptions that occur in cancer, the implications for cancer therapy are becoming increasingly evident. Unlike genetic mutations, epigenetic changes are potentially reversible. This raises the possibility that drugs capable of returning epigenetic markers to their normal setting could be extraordinarily effective in cancer. A few such drugs have already been approved for certain cancer types, and dozens more are being tested in clinical trials.
Learn more about cancer research from Dana-Farber."