Just saw this article. I don't think it says anything that we don't know already, i.e., more aggressive combination therapies are significantly better than ADT alone for the advanced disease.
However, I found myself looking back at the original CHAARTED results, and their OS projection in particular. Let me just make it clear that I'm not obsessing over the OS numbers by any means - they're - among other issues -outdated and backward looking. But a question that I have is this: did the study keep the patients only on ADT or ADT+Docetaxel throughout all the way to the OS event despite progression? I can't see any information on additional treatments - just curious how this number is calculated.