I am seeking info for my brother. He has advanced MCRPC. Two years ago he began with hormone treatment which did not work. Followed with zytiga which did not work. Followed with radiation which was not very effective. Just finished the fourth dose of docetaxel. Tests show it is not working, so it is being discontinued. Onc wants to try xtandi now. Also mentioned that there is one other chemo drug to try (assuming it is cabazitazel). From various reports in various journals, it seems that the odds of the xtandi helping at this point are slim. I am also under the impression that the cabazitazel is used as a follow on to the full course of docataxel. It seems to me that zofiga combined with the xtandi is his last hope. Can anyone PLEASE help with any info?