Seeking clarity for the recipe for th... - Advanced Prostate...

Advanced Prostate Cancer

22,373 members28,142 posts

Seeking clarity for the recipe for the magical cocktail: ursolic acid, reservatrol and curcumin

Kuanyin profile image
7 Replies

To shed a little light on our discussion of the Ursolic Acid, Reservatrol and Curcumin cocktail, I took the liberty (copy of email appears below) to one of the authors of the paper we gave been discussing. It's been my experience, that research scientists often choose not to answer or their answers are very "guarded," for obvious legal reasons. However, should the researcher reply, I will post it.

"Dear Professor Lodi,

I am a member of HealthUnlocked a discussion forum for people with advanced

prostate cancer. One of the participants recently posted a link to your research

paper "Combinatorial treatment with natural compounds in prostate cancer

inhibits prostate tumor growth and leads to key modulations of cancer cell

metabolism." The content of the paper has created quite a stir among

participants who are eager to apply some of your findings in their own regimens.

I'm sure you are quite aware that people with serious diseases are always on the

look out for less toxic ways of managing their illnesses. Since most of us

already take curcumin and resveratrol, it would be easy to add ursolic acid.

However, there is a great discussion going on how to combine these three

substances so that a "therapeutic" dose is achieved. It's not easy, though,

translating the units used in the study (ug ml, ug dl, etc.) into something a

layperson understands; nor is it easy to go from test tube and studies with mice

to human beings. This is our problem. Thinking in terms of mg and grams, which

most of us are used to, it is almost impossible to make the leap. For example, I

recently read somewhere, I believe it was a University of Utah study, that the

amount of ursolic acid we would need for a therapeutic effect would be

approximately 2% of a day's intake of food. Using apples (with each apple

calculated at 100 grams), it would take about eleven apples to supply that much

ursolic acid. Different research papers are all over the map when it comes to

curcumin (three grams?) and resveratrol (250-500 mg?). Probably these amounts

would be reduced because of the synergy between these three nutrients. But,

again, there are the issues of "purity" (standardized to what?) and

bioavailability. Members of the Forum have different suggestions about which

product is the most bio-available and what strength and standardization to use.

It's almost all anecdotal.

What we would like to ask of you Professor Lodi, and your fellow researchers, is

to provide us with some kind of "guidance" regarding these issues I have

outlined above.I realize that your paper is just the initial step in the

research process until the gap between animal studies and Homo sapiens is closed

and that you cannot make outright recommendations (for legal reasons, I'm sure),

but whatever guidance you may provide would certainly be appreciated by all of

us!

I will post a copy of this email on our website, but should you reply, I will

also post your reply on our website. Thank you.

Best wishes, (name removed)

Written by
Kuanyin profile image
Kuanyin
To view profiles and participate in discussions please or .
Read more about...
7 Replies
Burnett1948 profile image
Burnett1948

Burnett1948. Thanks Kuanyin for doing this.

Scruffybut1 profile image
Scruffybut1

Thanks Kuanyin for that info.

erjlg3 profile image
erjlg3

Thanks so very much Kuanyin :)

RJ-MN profile image
RJ-MN

Very nicely written!

zdanez profile image
zdanez

Awesome! Thanks for doing this. It will be interesting to see of we get a reply.

Dane

4luvofrob profile image
4luvofrob

A very nicely composed letter! I hope that you receive a reply; I know everyone on the

site will look forward to reading it. Thank you.

charmander profile image
charmander

thanks for your efforts! well written

Not what you're looking for?

You may also like...

Part 2: Report on the Ursolic Acid, Curcumin & Resveratrol Cocktain

As you know a couple of weeks ago, I wrote an email to a Professor Lodi listed on the paper...
Kuanyin profile image

I Previously Posted On The Benefit Of Ursolic Acid - Curcumin - Resveratrol In Treating PCa..Here Is How The Combo Works

The amazing fact was that the combo was as effective as Chemo. I could not find a safe supply of...
gusgold profile image

Inhibition of estrogen signaling through depletion of estrogen receptor alpha by ursolic acid and betulinic acid from Prunella vulgaris var.

I really didn't want to get into a citations war where the results of one paper are immediately...
Kuanyin profile image

How to starve cancer by jane Mclelland

In the book Jane lists various cocktails as supplements to conventional treatments.... I would like...
Karmaji profile image

Some Difficulties Translating Scientific Studies into News We Can Use

I recently re-read a paper that was discussed in this forum over a year ago. I bring it up now...
Kuanyin profile image

Moderation team

Bethishere profile image
BethishereAdministrator
Number6 profile image
Number6Administrator
Darryl profile image
DarrylPartner

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.