As many here know, I'm on Lupron and Zytiga. My PSA was hovering around 1, about six months ago. It started to go up by .2 increments, and today is 2.5. Just two months ago, I asked my Onc, when should I be concerned over the increases? He said, "Not until it doubles." I'm thinking that that had happened when it hit 2, a few months back. I always had to call my Onc's office the next day to get my PSA result, and was quite surprised when I saw a message from them this morning. When she told me it hit 2.5, I was like "WHAT?" And, I was informed that I have to have my imaging done exactly when it was planned for anyway. As a side note here, I started BIRM on May 1.