Introduction

[terp]

Hello, im terp. Short for terpstra, which is dutch and they say if your not dutch, your not much! LOL.

Anyway i have 3 brothers and two sisters. A wonderful wife, and 5 children, from 26 to 14 years old. i moved to Vero Beach fl. from NJ in 2009. Presently employed at Johns Island Club as head carpenter.

i was diagnosed with stage 4 prostate in 2013 which has metastasized to spine etc..went through and still on hormonal treatment. prescription pills to knock down testosterone levels (failed), and three months chemo (failed) and a heavy duty chemo for another 3 month term and it too failed. now given xtandi, which will start soon. have doctors in Vero Beach fl , Tampa (moffit) and Texas (MD Anderson). will see what happens.

[Hidden]

Term I wish the best for you. Not sure what chemo you have had or who you are seeing with MD Anderson in the Texas Medical Center. I do know that Dr. Robert Amato with Memorial Hermann and also a professor with the University of Texas Medical School is a specialist in Prostate Cancer. He is in academia and is a Researcher. He is my guy.

I too was Stage 4 with mets to T3 and L2 of my spine 13 years ago in 2004. My chemo trial with him was six months. I took my last Lupron injection seven years ago and remain undetectable with no sign of cancer. He is certainly worth a consult.

Your Medical Oncologist at MD Anderson will know and you might ask him about the protocol that Dr Amato uses. It is not standard. I have put the protocol up in this group. Simply search or I can send to you.

Good luck in fighting this bastard.

Gourd Dancer

[skateguy in reply to Hidden]

I would be interested in knowing the protocol that gave you this great outcome. Thanks

[Hidden in reply to skateguy]

Skatebuy, I have posted. Good luck brother.

GD

[fco1969 in reply to Hidden]

Buenas tardes gourd_dancer.

He oído hablar del Dr. Robert.

Amato y su profesionalidad. Me puedes enviar tu

¿¿¿protocolo???

Gracias

[Hidden in reply to fco1969]

Bien gracias. Buenas tardes a ti también.

Los pacientes inscritos recibieron ADT en forma de leuprolide cada 12 semanas durante 24 meses con bicalutamida iniciando después de la finalización de la quimioterapia. Un ciclo de quimioterapia consistió en ketoconazol y doxorrubicina durante las semanas 1, 3 y 5 y estramustina y docetaxel y durante las semanas 2, 4 y 6. Durante las semanas 7 y 8, no se recibió tratamiento. Hubo 3 ciclos para un total de 6 meses. Además, cada día de la prueba, tomé 30 miligramos de prednisona.

Puede buscar en Internet: "Una prueba de fase II de la terapia de privación de andrógenos (ADT) más quimioterapia como tratamiento inicial para fallas locales o cáncer de próstata avanzado" Agregar, "Robert Amato"

Gourd Dancer

[fco1969 in reply to Hidden]

okay. thank you

[Hidden]

Research "A phase II trial of androgen deprivation therapy (ADT) plus chemotherapy as initial treatment for local failures or advanced prostate cancer" Add, "Robert Amato"

Published in Cancer Chemother Pharmacol. 2013 Jun;71(6):1629-34. doi: 10.1007/s00280-013-2163-4. Epub 2013 Apr 21.

"Forty-six patients were enrolled, and forty-five patients were evaluable. Median progression-free survival (PFS) was 23.4 months. Median overall survival (OS) was 53.7 months. Out of 45 patients with measurable disease, 22 patients had an objective response: 9 patients achieved a complete response; 2 patients achieved a partial response; 10 patients achieved stable disease. Frequent grade 3 adverse events included elevated ALT (17 %), hypokalemia (13 %), and hypophosphatemia (13 %). Grade 4 adverse events were rare and included low bicarbonate (2 %), hypokalemia (2 %), leukocytopenia (2 %), and neutropenia (2 %)."

Gourd Dancer

[Hidden]

A phase II trial of androgen deprivation therapy (ADT) plus chemotherapy as initial treatment for local failures or advanced prostate cancer. Enrolled patients received ADT in the form of leuprolide every 12 weeks for 24 months with bicalutamide initiating after the completion of chemotherapy. Chemotherapy consisted of ketoconazole and doxorubicin for weeks 1, 3, and 5 and estramustine and docetaxel and for weeks 2, 4 and 6. During weeks 7 and 8, no treatment was received.

Gourd Dancer

[JoelT]

What do you mean by "Failed?" Advanced prostate cancer is not curable, I hope that the docs have been honest with you.

Joel

[Hidden in reply to JoelT]

Joel, after 13 years several Stage 4 like me are proving your statement wrong. I believed that until about six months ago and after another series of bone scans and softissue CT scans, I finally am in agreement with my Medical Oncologist. He can find no sign of cancer in my body. A tremendous amount of research has taken place and will continue to take place. It is what it is. Started the APCa journey just wanting to play the waiting game like many others. I have been very fortunate to be admitted in a chemo trial program immediately after the discovery of mets. Frankly, it means hope in kicking this bastard.

GD