Transdermal estrogen patches are sometimes used as an alternative to the traditional Luteinising Hormone-Releasing Hormone Agonists (i.e. Lupron, etc.) drugs for hormone therapy (ADT). Patches are successful in castrating a man, but unlike the LHRH agonists don’t cause bone mineral density loss. This is important because bone health is vital in fighting prostate cancer.
See the Malecare Advanced Prostate Cancer Blog: