A blessing and curse of prostate cancer is it is often slow moving. The blessing and curse of the US FDA is it is always slow moving. What I can find on the status of transdermal estrogen for prostate cancer is it has not been approved (yet). If there is a newer FDA approved drugs list please let us know.
January 2021 FDA approved drugs for prostate cancer.
January 2021 Lancet article on PATCH (transdermal estrogen) trial results.
February 2021 Physican Weekly notice of PATCH testing results.
The FDA cannot approve estrogen patches until the trial has published the results. They have only published the cardiovascular results but not the efficacy outcomes. They usually publish after a big meeting like the EAU conference in March. After publication, it will take about a year for the FDA to go over all the data with a fine-toothed comb.
Thank you. In northern Ohio there’s a Wooly Bear caterpillar celebration soon. They race caterpillars. Slow race. Start to finish maybe a foot. As I wrote, diligence to protocols is a blessing and a curse. Seems overall good for Abbot, Bauer AG, etc. Again, as always, thank you.
PATCH/STAMPEDE is a UK trial. Because of the cost savings, NICE would be eager to approve it when published. But, as I said, they have only published toxicity results, not efficacy results, so NHS cannot approve a drug of unknown efficacy. FDA has been criticized for rushing to approve drugs before thorough analysis of the data - we, as patients, can't have it both ways.
Isnt this a bit of “back to the future”? I recall oestrogen was a treatment protocol decades ago and went out of favour due to toxicity and LHRH animists being superior. What’s the rationale for testing it again?
Prior oral use of estrogen involved harmful effects to liver and heart. The transdermal patch eliminates those effects. “Substitution of estrogen patches for luteinizing hormone-releasing hormone agonist therapy in men with castration-resistant prostate cancer has similar testosterone-depleting effects while improving metabolic side effects, according to results from the PATCH trial.” cancernetwork.com/view/estr...
To the best of my knowledge tE2 has not been approved in The US. There is too much money to be made with doctor visits and ADT injections! Richard Wassersug has been buying it in Canada for $55 tube and he just told me that they have increased the price substantially. It is still less than $20 tube in Thailand. I haven't been to a doctor in four years...tE2 is working great for me with little boobs as my only side effect.
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