Hi, 2009 I had RAI treatment for Graves. The treatment worked!!! and now I have no thyroid function at all. I have been taking thyroxine since then and have felt quite well on a dose of 125,150mg alternate days. I have had regular readings taken of TSH and FT4 and these have been ranging TSH 0.03-0.24, FT4 18-25. I have had no overactive side effects, my pulse rate is good, no anxiety problems etc. My doctor keeps telling me to reduce, I was quite worried about the effect these readings were having on my body, so I have been on 125mg every day now for 2 weeks. Over the past 4 days I dont sleep very well, having lots of anxiety and the dredding "dark Cloud" has started to appear. I dont know what to do??? shall I just go back to my original dose??? Does the TSH reading really matter if your thyroid is dead??