On the NatureThroid site is stated: "Due to the higher bioactivity of natural thyroid, physicians may choose a slightly lower dosage to achieve similar results for patients converting from synthetic thyroid." I'm wondering whether this is because of the higher proportion of T3?? Pigs make more T3 than humans do so that natural products aren't quite the right proportion.
Those of you who have switched to the natural, how did you determine how many grains to take? Do any of you supplement with extra synthetic T4? Did it take you very long to adjust to the change?