This paper looks at the 2011 guidelines and reassesses advice. In general, recommendations are lower.
Still no acknowledgement of vitamin D intolerance issues.
However, some impressive graphics!
Revisiting Vitamin D Guidelines: A Critical Appraisal of the Literature
Michael F. Holick, PhD, MD
Abstract
Background/Objective
The goal of this review is to compare the 2024 and 2011 Endocrine Society’s Clinical Practice Guidelines on vitamin D2 or vitamin D3 (vitamin D). The 2024 Guideline made recommendations for the general healthy population for skeletal and extra skeletal health benefits of vitamin D. This contrasts with the 2011 Guidelines which provided clinicians with guidance on how to evaluate and treat patients with vitamin D deficiency and prevent recurrence.
Discussion
The 2024 Guideline focused on randomized controlled trials and ignored association studies and other studies that have supported the skeletal and extra skeletal health benefits of vitamin D. The 2024 Guideline recommended empiric vitamin D in children and adolescents aged 1 to 18 years to reduce risk of upper respiratory tract infections, pregnant women to improve pregnancy-related outcomes, prediabetic patients to reduce risk of diabetes, and to improve mortality in those over 75 years.
Conclusion
These guidelines do not apply to individuals with abnormalities in calcium, phosphate, vitamin D, and bone metabolism which were provided in the 2011 Guidelines. For nonpregnant adults up to the age of 75, they recommend the Dietary Reference Intakes of 600 IUs (international units; 1 IU = 25 ng of vitamin D), and 800 IUs as recommended by The Institute of Medicine. Association studies have suggested that to obtain maximum extraskeletal benefits from vitamin D including reducing risk of upper respiratory tract infection for children and adults, autoimmune disorders, pre-eclampsia, low birth weight, neonatal dental caries, and deadly cancers circulating concentrations of 25-hydroxyvitamin D should be at least 30 ng/mL with a preferred range of 40-60 ng/mL as recommended by the 2011 Guidelines.
Keywords
vitamin D
2024 Vitamin D Guidelines
2011 Vitamin D Guidelines
extra skeletal health
25-hydroxyvitamin D
Highlights
• Perspective of 2024 Endocrine Society’s Guidelines on Vitamin D compared to and contrasted to the 2011 Endocrine Society’s Guidelines
• Reviewed the 2024 Guidelnes Vitamin D for the Prevention of Disease: For public health and extra skeletal health
• Reviewed associations’, and other studies that support a serum concentration of 25-hydroxyvitamin D of at least 30 ng/mL, for bone health and extra skeletal health benefits
• How much vitamin D is required to maintain a 25-hydroxyvitamin D in the preferred range of 40-60 ng/mL for maximum health.
Clinical Relevance
This review compares and contrasts the 2024 Endocrine Practice Guidelines on Vitamin D with the 2011 Endocrine Practice Guidelines. It provides guidance for the evaluation, treatment, and prevention of vitamin D deficiency for skeletal and nonskeletal health and maintaining a circulating concentration of 25-hydroxyvitamin D of at least 30 ng/mL.
If you download the full issue, you are warned you have to sign in to get everything. But I successfully got the PDF of this article - and several others.
Confused about Vitamin D levels.
Another reason for increasing Vitamin D level
