Diagnosed Hypothyroidism one year ago and have "levelled" on 50mg Levothyroxine TEVA brand. Fluctuating symptoms ongoing, although definitely an improvement from one year ago.
My neutrophils and lymphocytes are too low, and fluctuate within the too-low range, with bloods every 6 months. This was a feature pre-diagnosis too. Does anyone know if this is a feature of Hypothyroidism in some way or for any reason?
My GP seems puzzled and the hematologist recommends 6 monthly bloods and referral if my mouth becomes sore.
Any light on the subject welcome, in relation to Hypo.
Many thanks
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PorridgeFanatic
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Please add most recent thyroid and vitamin results and ranges
You are legally entitled to printed copies of your blood test results and ranges.
Just testing TSH is completely inadequate
For full Thyroid evaluation you need TSH, FT4 and FT3 tested
Also both TPO and TG thyroid antibodies tested at least once to see if your hypothyroidism is autoimmune
Very important to test vitamin D, folate, ferritin and B12 at least once year minimum
Low vitamin levels are extremely common when hypothyroid, especially with autoimmune thyroid disease
About 90% of primary hypothyroidism is autoimmune thyroid disease, usually diagnosed by high TPO and/or high TG thyroid antibodies
Autoimmune thyroid disease with goitre is Hashimoto’s
Autoimmune thyroid disease without goitre is Ord’s thyroiditis.
Both are autoimmune and generally called Hashimoto’s.
Significant minority of Hashimoto’s patients only have high TG antibodies (thyroglobulin)
20% of autoimmune thyroid patients never have high thyroid antibodies and ultrasound scan of thyroid can get diagnosis
In U.K. medics hardly ever refer to autoimmune thyroid disease as Hashimoto’s (or Ord’s thyroiditis)
Essential to test vitamin D, folate, ferritin and B12
Lower vitamin levels more common as we get older
For good conversion of Ft4 (levothyroxine) to Ft3 (active hormone) we must maintain GOOD vitamin levels
What vitamin supplements are you taking
VERY important to test TSH, Ft4 and Ft3 together
What is reason for your hypothyroidism
Autoimmune?
Recommended that all thyroid blood tests early morning, ideally just before 9am, only drink water between waking and test and last dose levothyroxine 24 hours before test
This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip)
Private tests are available as NHS currently rarely tests Ft3 or all relevant vitamins
Levo doesn’t “top up” your own thyroid output, it replaces it
Most important results are ALWAYS Ft3, followed by Ft4 and GOOD vitamin levels
Always test early morning and last dose Levo 24 hours before test
Guidelines of dose Levo by weight
approx how much do you weigh in kilo
Even if we frequently start on only 50mcg, most people need to increase levothyroxine dose slowly upwards in 25mcg steps (retesting 6-8 weeks after each increase) until eventually on, or somewhere near full replacement dose (typically 1.6mcg levothyroxine per kilo of your weight per day)
Adults usually start with a dose between 50 micrograms and 100 micrograms taken once a day. This may be increased gradually over a few weeks to between 100 micrograms and 200 micrograms taken once a day.
Some people need a bit less than guidelines, some a bit more
TSH should be under 2 as an absolute maximum when on levothyroxine
If symptoms of hypothyroidism persist despite normalisation of TSH, the dose of levothyroxine can be titrated further to place the TSH in the lower part of the reference range or even slightly below (i.e., TSH: 0.1–2.0 mU/L), but avoiding TSH < 0.1 mU/L. Use of alternate day dosing of different levothyroxine strengths may be needed to achieve this (e.g., 100 mcg for 4 days; 125 mcg for 3 days weekly).
Many previous studies have confirmed the close association between lymphocytes and hypothyroidism [9, 11]. Lymphocytes are involved in the process of hypothyroidism, especially in autoimmune diseases of the thyroid, such as Hashimoto's thyroiditis.
Oh sorry I also have the low white blood cells and it makes you feel so weak as if you are anaemic. I was told my WBC is good but tbat is low and to continue taking the iron pills. So strange. I asked the doctor what causes that and he said maybe some type of infection, but he couldn't identify it. I don't what to say, except that I hace noticed thst our diet and surroundings have a lot to do with how we feel.
Thank you blackcake, I appreciate your response ... I too feel "anaemic" although my iron levels show within the normal range on bloods. All very strange.
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