High TRAb and low TSH

[calej]

Hello!

After battling Graves since 2016, I'm finally off meds (T3 and T4 are normal) but my TSH is LOW 0.30 mIU/L and my TRAb is high 6.3 IU/L.

Would anyone know how to fix these values and if they are important at all? I'm totally feeling great and healthy with no issues. My back pain is gone, lost the extra weight, energy is back in full force and hair is growing back (medicine side effects).

Any input would be highly appreciated!

Thanks!

[jimh111]

TRAb can suppress TSH a little as they mimic TSH and the pituitary has a paracrine mechanism whereby TSH plays a minor feedback role in suppressing secretion of TSH. It's also possible that your fT3 and fT4 are slightly high and this lowers your TSH. It's probably the former and a TSH of 0.3 isn't articularly low so not a problem.The is evidence that selenium supplementation helps lower TRAb, not massively but a useful contribution.

[calej in reply to jimh111]

thank you! I will look into this. This is very helpful.

[pennyannie]

Hey there again :

When did you stop the Block & Replace regime ?

The TSH in Graves Disease is a very unreliable measure of anything when taking any form of medication and you must be dosed and monitored on your Free T3 and Free T4 readings :

Graves antibodies circulate in your bloodstream and tend to ' get ' stuck ' on the TSH follicles causing the over production of thyroid hormones - which in turn causes Graves Disease.

Your Trab reading looks high - is this the current reading now you are off the AT drugs - as it appears your immune system is still in an active phase and you may experience further issues.

calej Please reread what I have written above - as I think I may have confused you.

[calej]

hi! I stopped meds 2 months ago. I was first diagnosed more than 10 years ago and Trab was not even included in the test sorry.

[pennyannie in reply to calej]

So, treatment with B & R stopped 2 months ago - were your TRab run before coming off this treatment option ?

If still with high o/range TRab your immune system is still active and you may find you have a repeat episode of unwellness.

I think you need to reread my previous reply as I have rewritten it - a bit - as I think what I had previously written was confused.

[calej in reply to pennyannie]

Hello! My TRAb before I stopped meds was still high 5.9 iu/l and TSH normal at 2.77 (My T3 was normal at 2.5 and T4 was low at 0.8 ng/dl The months before that all had high TRAb values as well.

[pennyannie in reply to calej]

Do you ranges for the TRab, T3.and T4 please ?

Well it's encouraging that you TSH is now well in the range - almost too high now !! and a sign that your Graves not currently active as that tends to show as a low suppressed TSH :