Mounjaro after Thyroidactomy

[Shefaa]

Hey guysI have Hypothyroidism sincec the time I was born. I am taking medicin for it on a daily basis since then.

I got maried and had 3 kids, with bregnance and all of that my tsh were getting affected so some tomes my thyoid would swells and you might see a ball popping out in my neck.

I did some ultrasounds and it also showed that I have some benign nudules on my thyroid.

After thinking and cosulting with a general sugent, we decided to the sugery.

I had my thyroidactomy two years ago, and I am still on medicin and no problems thank god.

I had my forth baby 5 months ago, and now I really want to loose the weight that I build with these pregnencies.

I am thinking to take mounjaro, However I am a little nervous, because I do not know the aspect of this on me, and wheather there are any side effect.

Who took mounjaro after a Thyroidactomy?

And what issues have you faced?

Kindly tell us about your experience. ❤️😊

[butterflynett]

I haven't had a thyroidectomy, but I am hypothyroid and have taken Mounjaro. It mostly affects your digestive system (nausea, diarrhea or constipation). It also caused a temporary rash at the injection site sometimes that would have to be treated with a topical antihistamine cream. I didn't take it for long so can't attest to any long term effects.

[Redditch]

I am on it now. 5 months in. 12 kilos lost I quit my job and ended my relationship. I swear it's changed my personality. I am not stroppy but I'm definitely more resolute.

I can't food shop. This might be an issue for you.

I didn't realise how much my food shop is based on my appetite.

I started with 25 which is the lowest dose and in that month I was eating 2 meals a day I then went to 50 and I didn't eat at all so I went back to 25.

I have my jab Monday night so Sunday and Monday are near normal appetite. Tuesday will be suppressed and I won't eat much a tall on Wednesday Thursday Friday suppressed appetite Saturday then Sunday and Monday normal. So it works just like the 5:2 diet.

I just don't think about food.

[Mummybear0213 in reply to Redditch]

Do you mean 2.5 and 5 in relation to the dosages?

[Redditch in reply to Mummybear0213]

Yes

[Mummybear0213]

I've not had the procedure you've mentioned but I have used Mounjaro and it worked wonders for me. I only needed to use it for 2 months because I lost over 2 stone so quickly. The side effects differ for everyone. I thankfully didn't experience anything too bad.

Like you I struggled losing the pregnancy weight after 4 kids in the space of 6 years 😬

But - and it's a big but......I recently read that Mounjaro causes thyroid CANCER in a study with mice. Soo that's probably something to bear in mind whether you have thyroid problems or not.

I'll find the study and share the link.

[Mummybear0213 in reply to Mummybear0213]

It's not pasting for me 🤦🏻‍♀️

but a quick Google brings up plenty of info and a small study.

You only have to click on the Lilly website (Mounjaro manufacturer) and a big warning comes up 😬

Lilly Thyroid cancer warning

[Redditch]

Ozempic had a mild increase in Thyroid cancer but Mounjaro has 2 ingredents and both different from Ozempic.. I had a scan on my thyroid to check I had no nodules before I started

[StitchFairy in reply to Redditch]

If you google the words 'Mounjaro cancer', there are lots of links warning that it may cause thyroid cancer.

[Mummybear0213]

Sorry OP, not meaning to scare you! I just learnt the cancer risk myself recently so maybe I'd have thought twice before using it.

Maybe it applies to long time users? Who knows. I suppose a lot of medications have risks, it's up to the patient if they want to take that risk I guess.

[Shefaa]

Actually the reason I asked about mounjaro is because I heard that it could cause thyroid cancer, that was the main thing for me. However I have already removed my thyroid, so I wanted to know if anyone removed the thyroid and cosulted the doctor regarding mounjaro. (as maybe no thyroid so no cancer🫣)

[RedApple Administrator in reply to Shefaa]

No-one here is medically qualified, and therefore cannot answer your question Shefaa.

You must consult your own doctor for advice about your own situation.

[Tina_Maria in reply to Shefaa]

Just to clarify, if there is a risk something can cause cancer, it does not mean that you definitely will get cancer. It is also dependent if the risk is high or low. As these newer medications are now used to lose weight (they were primarily developed to control glucose in diabetic patients), they are still under surveillance and all adverse effects have to be reported, even if there are only a few cases.

I have found a recent publication in the BMJ analysing risk of thyroid cancer in patients using GLP-1 agonists (cohort study):

bmj.com/content/385/bmj-202...

Conclusions: In this large cohort study using nationwide data from three countries, GLP1 receptor agonist use was not associated with a substantially increased risk of thyroid cancer over a mean follow-up of 3.9 years. In the main analysis comparing GLP1 receptor agonists with DPP4 inhibitors, the upper limit of the confidence interval was consistent with no more than a 31% increase in relative risk.

[Tina_Maria in reply to Shefaa]

I had another quick look and there are other publications that suggest an increased risk of thyroid cancer after prolonged GLP-1 therapy. However, these are patients who are on very long regimens of GLP-1 therapy for more than 6 years (diabetic patients), where as if these medications are prescribed for weight loss, their use is usually much shorter and therefore you would have less exposure (and hence a lower risk).

diabetesjournals.org/care/a...

You need to discuss the risks and benefits of GLP-1 therapy with the GP and then make a decision based on the information you have.