Experiences with methylprednisolone injections ... - Thyroid UK

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Experiences with methylprednisolone injections and methotrexate while on levo

Flaxjax profile image
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Hi everyone, just diagnosed with Psoriatic Arthritis and yesterday was given a Methylprednisolone intramuscular injection and about to be put on Methotrexate to control condition. My question is, the methylprednisolone injection says use with caution in patients with Hypothyroidism (me, 125ug levo daily), does anyone know what it does to thyroid levels? And anyone with experience to share of methotrexate with Hypothyroidism... Want to be prepared as much as I can! Thank you ❤️

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Flaxjax
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gabkad profile image
gabkad

All I know is if someone goes on a steroid like prednisone chronically, the dose of levo needs to be increased.

'Do steroids affect thyroid medication?

Corticosteroids can sometimes cause hypothyroidism or make it worse. High doses of prednisolone can slow the conversion of the thyroid hormone to the more active form.'

jclinmedcasereports.com/art...

Corticosteroid induced Hypothyroidism and Cushing's

syndrome: A Case Report

Flaxjax profile image
Flaxjax in reply togabkad

Hi, thx for the link, yes I'd read that it can reduce TSH secretion so that's one to keep an eye on!

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