Hi,
since 2 weeks I started to take 10 mcg T3/ 2 days on top of my daily levothyroxine.
I remember my periodic cycle was 24 days instead of 28 days when TSH was rising before. Today I was surprised to get my period at d23?!
I am confused again. Was expecting the opposite.
Isn't the whole idea. to split your T3 into 3 to 5 Doses and take it at the same time every single day? According to Paul Robinson's book Recovering with T3 this is what he says.
I didn't mean to say it like that♡
Depends on the person. Although I do think splittinginto 5 is a bit extreme!
Some people need to take it all in one go to flood the receptors. I take my 75 mcg all in one go and don't feel in the least that it's too much. Other people need to split it into 2 - sometimes 3 - doses.
But, Balou23, I don't know what you mean by I started to take 10 mcg T3/ 2 days on top of my daily levothyroxine. Do you mean you take it only two days a week? That's never going to work. You have to take the same amount every day with T3.
Thank you again GreyGoose for your reply!!!
I take T4 every day and T3 every 2 days because T3 has a half-time of 2 days.
I tried to split it in parts the first week, but it wasn’t easy and I didn’t manage to take small parts always at the same time.
Well, no, it doesn't.
T4 has a half-life of about a week. T3 has a half life of about 24 hours. But even if what you say were correct, it still wouldn't make sense to dose the way you're doing it. You absolutely have to take the same amount of T3 every single day if you want it to do what it's supposed to do: i.e. reopen the the receptors that were shut down during the time you were low in T3, get some T3 into them, and build up the correct amount inside the cell to stop your symptoms. Your doctor seems to be confusing T3 with aspirin!
So, I better take 5 mcg every day instead of 10 mcg every 2 days.
Do you think it is the right dose of T3 when taking 43,75 mcg T4 (average)? Ratio more or less 1:10?
Peri-menopausal? This will mess with your cycle timings 🤗
it’s going to take at least 6-8 weeks for dose to have effects
Presumably you mean you are taking 5mcg twice a day, every day
Retest after 6-8 weeks
Recommended that all thyroid blood tests early morning, ideally just before 9am, only drink water between waking and test and last dose levothyroxine 24 hours before test
This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip)
On T3 - day before test split T3 as 2 or 3 smaller doses spread through the day with last dose 8-12 hours before test
personally I still find it best to take as 5mcg doses (four times per day)
we are all different
I am taking 10 mcg or half of tablet every 2 days. Since I was taking alternately 50 mcg levo or 1 pink tablet and 37.5 mcg or half of grey tablet (Christiaens) I take it together with the lowest dose.
Well you absolutely can NOT do that
Any T3 it’s absolutely essential to take exactly same dose everyday, and preferably at roughly same time every day
Suggest you take 5mcg T3 everyday for 6-8 weeks
I really like this reply!
You really need to get Levothyroxine dose higher BEFORE adding T3
You increased to 75mcg too soon
At least 6-8 weeks on 50mcg …before retest
Once blood test shows need increase, then up to 75mcg …..wait at least 6-8 weeks and retest
Often won’t be ready to increase until been on constant unchanging dose and brand at least 12-20 weeks
How much do you weigh in kilo,
pathlabs.rlbuht.nhs.uk/tft_...
Guiding Treatment with Thyroxine:
In the majority of patients 50-100 μg thyroxine can be used as the starting dose. Alterations in dose are achieved by using 25-50 μg increments and adequacy of the new dose can be confirmed by repeat measurement of TSH after 2-3 months.
The majority of patients will be clinically euthyroid with a ‘normal’ TSH and having thyroxine replacement in the range 75-150 μg/day (1.6ug/Kg on average).
The recommended approach is to titrate thyroxine therapy against the TSH concentration whilst assessing clinical well-being. The target is a serum TSH within the reference range.
……The primary target of thyroxine replacement therapy is to make the patient feel well and to achieve a serum TSH that is within the reference range. The corresponding FT4 will be within or slightly above its reference range.
The minimum period to achieve stable concentrations after a change in dose of thyroxine is two months and thyroid function tests should not normally be requested before this period has elapsed.
The trouble with starting T3 too soon is that it will almost always totally suppress TSH, and if not on full replacement dose levothyroxine FIRST, you become more hypo
Also essential to maintain optimal vitamin levels
Interesting.
If TSH is suppressed by T3 non or less T4/T3 will be produced by the remaining half thyroid. If T4 intake is not sufficient you will become hypo, but is T3 which is active T4 not covering it up? If you take high dose of T4 TSH will also get lower and body will also stop producing T4/T3.
What do you mean by ‘increased to 75 mcg too soon’? I was on 50 mcg for 2 months, then I increased to 50/75 mcg (1 pink tablet and 1 grey tablet every other day) for 2 years. Then I tried to got to 75 mcg daily, but I had some signs of being hyper (hart rate, sweating, losing more hair). I also suffered from insomnia, even on 50/75 mcg, but my TSH was never low, only T4 went up. I decide to lower the dose to get some sleep again. I now am taking 50/37,5 mcg T4 and every other day 10 mcg T3.
tried to got to 75 mcg daily, but I had some signs of being hyper (hart rate, sweating, losing more hair).
Perhaps low iron / ferritin = hair loss
Sweating = low B12
Approximate how much do you weigh in kilo
When were vitamin levels last tested
You can NOT take different doses of T3 on different days
Strongly recommend you change to 5mcg per day
Perhaps as 2 x 2.5mcg
Hi, I weigh approx. 58kg
I am now taking T3 for 2 weeks and I noticed to great despair eyebrows are thinning again Eyes are very watery when I try to fall asleep which causes under eye bags.
Should I reduce dose slightly? T3/T4 combination therapy
starting t3, t4 combination 
Fluctuating Symptoms with T3/T4 combination
Studies on TSH for those on combined T3 T4 therapy 
