Can an excess of carbimazole (hyperthyroid medi... - Thyroid UK

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Can an excess of carbimazole (hyperthyroid medidaction) cause high triglycerides? How long does it take to normalise levels?

SusaM profile image
2 Replies

Last February 2023 I was diagnosed with hyperthyroidism, apparently autoimmune, and since then I have been taking carbimazole. It seems that the dose I was taking was too high (combining 10-20mg every 2 days) and last July I switched to hypothyroidism.

Since the beginning of October (the last 4-5 weeks) I have been taking carbimazole 5mg, and my thyroid now seems to be leaving swlowly hypothyroidism, but my blood test shows that my triglycerides are too high (2.6 mmol/L) and the GP wants me to take statins.

Somehow the carbimazole has given me hypothyroidism, so I would not like to start taking statins until the carbimazole dose is adjusted.

My doctor told me that after 10 months we would have another appointment and see if the autoimmune disease is temporary (as happened to my mother) or something permanent.

My questions are

How long does it take for my triglycerides to return to normal levels after adjusting my carbimazole medication and going to a normal thyroid profile?

I only had 1 phone call with my consultant to discuss medication in April, but no scan or thyroid palpation? is this normal or should I ask for a scan?

thanks

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SusaM
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SlowDragon profile image
SlowDragonAdministrator

Being hypothyroid will raise cholesterol and statins are NOT recommended

nhs.uk/conditions/statins/c...

If you have an underactive thyroid (hypothyroidism), treatment may be delayed until this problem is treated. This is because having an underactive thyroid can lead to an increased cholesterol level, and treating hypothyroidism may cause your cholesterol level to decrease, without the need for statins. Statins are also more likely to cause muscle damage in people with an underactive thyroid.

What are your actual results and ranges on thyroid including thyroid antibodies and vitamin levels

For full Thyroid evaluation you need TSH, FT4 and FT3 tested

Also both TPO and TG thyroid antibodies tested at least once

Very important to test vitamin D, folate, ferritin and B12 at least once year minimum

About 90% of primary hypothyroidism is autoimmune thyroid disease, usually diagnosed by high thyroid antibodies

Autoimmune thyroid disease with goitre is Hashimoto’s

Autoimmune thyroid disease without goitre is Ord’s thyroiditis.

Both are autoimmune and generally called Hashimoto’s.

Hashimoto’s frequently starts with transient hyperthyroid results and symptoms before becoming increasingly hypothyroid

were TSI or Trab antibodies tested for Graves’ disease (autoimmune hyperthyroid) when you had Hyperthyroid type results?

Low vitamin levels are extremely common when hypothyroid, especially with autoimmune thyroid disease ……Hashimoto’s or Graves’ disease

20% of autoimmune thyroid patients never have high thyroid antibodies and ultrasound scan of thyroid can get diagnosis

In U.K. medics hardly ever refer to autoimmune thyroid disease as Hashimoto’s (or Ord’s thyroiditis)

Recommended that all thyroid blood tests early morning, ideally just before 9am, only drink water between waking and test

This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip)

Private tests are available as NHS currently rarely tests Ft3 or all relevant vitamins

Testing options and includes money off codes for private testing

thyroiduk.org/testing/

Medichecks Thyroid plus antibodies and vitamins

medichecks.com/products/adv...

Blue Horizon Thyroid Premium Gold includes antibodies, cortisol and vitamins

bluehorizonbloodtests.co.uk...

Only do private testing early Monday or Tuesday morning.

Link about thyroid blood tests

thyroiduk.org/testing/thyro...

Link about Hashimoto’s

thyroiduk.org/hypothyroid-b...

Symptoms of hypothyroidism

thyroiduk.org/signs-and-sym...

Tips on how to do DIY finger prick test

See detailed reply by SeasideSusie

healthunlocked.com/thyroidu...

Medichecks and BH also offer private blood draw at clinic near you, or private nurse to your own home…..for an extra fee

Marz profile image
Marz

How was your Hyperthyroidism diagnosed ? Which anti-bodies were tested to confirm the diagnosis ?

I see you joined around 3 years ago so perhaps you have read here about the difficulties getting the correct testing/diagnosis.

If you are now hypo - why are you still taking carbimazole ? Getting the thyroid balanced could well sort the triglycerides.

Test results for B12 - Folate - Ferritin - VitD ? Do you have any ?

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