Antonio Bianco's recommendation for T3 dosage - Thyroid UK

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Antonio Bianco's recommendation for T3 dosage

MrPeaPaw profile image
11 Replies

I think I recently read here that Dr Bianco recommends a dosage range of 50mcg - 75mcg per day.

I've searched extensively but can't find this info. Does this ring a bell with anyone? I'd like to use it to bolster my chances of getting a small increase of liothyronine. I currently take 40mcg. Thanks!

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helvella profile image
helvellaAdministratorThyroid UK

I think they are less likely to increase your dose as you get older.

Not sure if their formula goes up to 138. :-)

More seriously, the Summary of Product Characteristics for 20 microgram liothyronine tablets say this (or close):

Starting dose of 10 or 20 micrograms every 8 hours, increasing after one week, if necessary, to the usual recommended daily dose of 60 micrograms in two or three divided doses.

mhraproducts4853.blob.core....

The USA equivalents say 75 micrograms.

The basis seems to be simply three tablets a day - but UK ones are 20, where USA ones are 25! So no pharmaceutical, medical, or other reasons. Just the simplest option.

That isn't what you asked for, but it might be useful.

Alanna012 profile image
Alanna012 in reply to helvella

Are these the recommended amounts of liothyronine for someone taking T3 only?

helvella profile image
helvellaAdministratorThyroid UK in reply to Alanna012

Let me phrase it slightly differently:

These are useful quotes from official documentation for liothyronine. to use if they suit you. They are bonkers. They clearly apply to T3-only. (No mention of any adjustment of previous dose, etc.)

Someone might need this much, less, or more. The fact it says "usual" implies there can be unusual cases!

And adjustment to a final dose might well need numerous small increments over a long time.

Alanna012 profile image
Alanna012 in reply to helvella

Thank you, that makes perfect sense!

jimh111 profile image
jimh111 in reply to helvella

I suspect these recommendations were knocked up with little knowledge. From my own experience and the evidence that liothyronine is 3x as potent as levothyroxine I would suggest a full dose of liothyronine is 40 to 60 mcg daily. It makes sense to stay on the lowest effective dose. With levothyroxine the deiodinases can to an extent protect against excess but with liothyronine this mechanism is partially bypassed.

It's plain daft that they recommend that you start on 3x 10 mcg daily and even dafter that you reduce this to 5 mcg daily when you become elderly.

TaraJR profile image
TaraJR

Yes he did say that in his webinar 'Rethinking Hypothyroidism'.

He also said that TSH should stay in range...

He is doing another webinar for The Thyroid Trust in June.. I think we should ask him questions pertaining to those things

thyroidtrust.org/events-lis...

diogenes profile image
diogenesRemembering in reply to TaraJR

And this is the crux of the matter! He simply will not let go of "normal range TSH" as a desired endpoint in treatment. Poliitically he can't let go, because the US medical world might just accept combination therapy over T4 only, the demolition of the TSH story is at the moment just too controversial and a step too far for him, given the sacred place it has had for 38 years. The need for correction to the thyroid story isn't simply admitting combination therapy but a complete overhaul. This has at its centre abandonment of the currently held beliefs about the value of TSH. As Corporal Jones said, "they don't like it up 'em."

TaraJR profile image
TaraJR in reply to diogenes

'They don't like it up em' indeed!! diogenes that is a classic!

But I suppose it's something that T3 is being talked about a lot more now, and Bianco is actually admitting that things have been wrong for way too long.

There will be questions asked re TSH on Thyroid Trust's zoom!

arTistapple profile image
arTistapple in reply to TaraJR

It surely must be getting more and more difficult and uncomfortable for endos speaking publicly not to expose the TSH myth and that of proper and useful T3 treatment with tailored dosing. We have seen the tantrum of the last president of The British Thyroid Association ridiculing patients publicly with his ‘fixed ideas’ on treatment with T3. It’s much easier (Ha) in the consulting room where it’s easy to intimidate a single desperate patient. I find it difficult to believe the likes of Bianco is unaware of this dilemma. However I am a person who still thinks honesty and integrity is important (naive). Surely someone as high profile as Bianco is preparing the ground for this big reveal at some point. Or is he as blind to the right thing to do as Pierce? I won’t hold my breath but …….

TaraJR profile image
TaraJR in reply to arTistapple

Animals/people are more dangerous when cornered...

"It’s much easier (Ha) in the consulting room where it’s easy to intimidate a single desperate patient." How terribly sad that I read that and agreed with you.

arTistapple profile image
arTistapple in reply to TaraJR

I wanted to say what you said re: cornered. Unfortunately the words failed to come at that moment. Well everything, no matter how slowly, seems to be more and more in open view with the likes of the work you are doing (which is very much appreciated). Today’s webinar could throw up some good stuff too.

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