T4+T3 Dosage Statistics: Hello, I am trying to... - Thyroid UK

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T4+T3 Dosage Statistics

Caesard profile image
6 Replies

Hello, I am trying to make something out of other people experiences.

If you are willing to share the numbers behind your story it would make sens in helping me and others to position themselves.

Therefore, peaople on T4 + T3 or T3 only, please let us know your demographic data, situational context (after RAI/TT or with Hashi/Graves) and dosage that offered the best symptom relief (low energy, brain fog, etc) or current dosage, associated conditions (if any) and other helpful inputs (e.g. D3, Fe, B12 supplementing & quantity)

Thank you so much, I give you my word I will centralize anonymously your results and send them to Admins for publishing!

For anonymity purpose, your responses can be sent to me via PM too!

Therefore

AGE

SEX

BMI: (body mass index) or WEIGHT if BMI unknown

THYROID Status

T4 quantity

T3 quantity

Symptom relief status

Associated Conditions

Supplements/Other helpful hints

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Caesard profile image
Caesard
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6 Replies
Caesard profile image
Caesard

AGE

- 37

SEX

- M

WEIGHT

- 94 Kg

THYROID Status - After TT (Graves)

T4 quantity

- 125-150 mcg/day

T3 quantity

- 30-40 mcg/day

Symptom relief status -

75% restored, relieved brain fog, better concentration and energy

Associated Conditions

- sluggish adrenals

Supplements/Other helpful hints - B12 for brain fog, D3 for joint pain and skin health

dang profile image
dang

Hey Caesard, interesting idea to gather info. I don't mind sharing if it can help others:

AGE: 31

SEX: M

WEIGHT: 70kg

THYROID Status: Hypothyroid (Hashimoto's)

T4 quantity: 100mcg

T3 quantity: 10mcg

Symptom relief status: Major Improvement: brain fog, cold intolerance, emotional stability, stamina, energy, sleep and sleep patterns. Moderate improvement: hair re-growth.

Associated Conditions: Histamine Intolerance (DAO enzyme deficient), Colitis, Duodenitis.

Supplements/Other helpful hints: TPO antibodies quite high (over 1000), TSH under range, FT3 top of range.

I hope this helps!

SeasideSusie profile image
SeasideSusieRemembering

Can I ask what you intend to do with the information and how it can help others?

Other than the fact that T3 can help some people, I'm struggling to understand how what doses someone takes can help anyone else as we're all different with individual needs. From the two replies here, one is taking T4 and T3 in the ratio of 10:1 and the other nearer 4:1

Can you explain further please?

Caesard profile image
Caesard in reply to SeasideSusie

Hello, you're right that individuality is a factor and it's also true that this effort will not be statistically relevant.

However, don't underestimate the relevance of data, even if it isn't statistical relevant, it will give an indication of min/max/avg usage of HTR components (quantity, ratio) and their correlation of symptom relief.

What's actually more important than the numbers behind is the fact that we are talking also about success stories here and, if taken individually, besides HRT components and dosage each one has some elements that allow a reasonable comparison (thyroid status, underlying disease, associated conditions, supplements) and advice. I need this and I needed it badly when I was worse and very unable to clearly make my own assessments and take informed decision.

Last but definitely not least, remember this is the silver bullet that brought us here together - SHARING INFORMATION and this is why most of us owe a lot to this site. Why sharing success stories or attempts/WiP would seem a bad idea?

Parbrook profile image
Parbrook

AGE: 66

SEX: M

WEIGHT: 66kg

THYROID Status: Thyroid gland knackered by treatment with Interferon Alpha (a known consequence).

T4 quantity: 50mcg

T3 quantity: 25mcg (mostly) or 30mcg (occasionally, based-on how I feel)

Symptom relief status: very good. Most symptoms gone with 75mcg T4 and 20mcg T3, but the move to 50mcg T4 and 25mcg T3 was the final step in getting rid of the remaining brain fog.

Associated Conditions: none

Supplements/Other helpful hints:

I am missing 1 kidney, spleen and remaining kidney virtually knackered (I'm on dialysis). Missing/knackered organs = less T4-T3 conversion.

Hence I have a good medical justification for adding T3 to T4.

I only have a thyroid blood test very occasionally. As long as FT4 and FT3 show my GP (and others) that I am not overdosing, I ignore the blood results and adjust my T3 according to how I feel. This works for me. My view is that too many people seem to believe that blood results are the drivers for dose decisions. However, there is no blood test in the world that can measure how much T3 is being absorbed at a cellular level and it is this level of absorption that drives the symptoms. So, symptoms rule!

Age: 58

Sex: female

Weight: 47.5kg

Thyroid status: Hashimoto's

T4: 75mcg

T3: 20mcg (Pointed out to endo that this was near to the 4:1 ratio produced by healthy thyroid)

Symptom relief status: Good! Joints no longer ache, not crushed by heavy tiredness, constant depressive mood has lifted etc. etc. The list is very long indeed.

Associated conditions: autoimmune response to gluten (as in coeliac) paid for comprehensive private test after advice from naturopathic practitioner to try gluten free - I was already vegan, so not keen - who gave me my DIO2 results (paid for this privately, too - and I'm not well off by any means, just desperately seeking better health. Have heterozygous form of this polymorphism - inherited from one parent). I had been refused T3 until I produced the results of this test. (Incidentally, like too many, I was very ill for decades before finally being diagnosed with Hashimoto's).

Supplements/helpful hints: If you have Hashimoto's (or any autoimmune condition), try going STRICTLY gluten free for at least a month if you can't afford the test. The NHS test only looks for one component of gluten and there are many, so may come back negative when you do have a serious problem with gluten, though worth a try if NHS will fund it. Some people have a kind of 'addiction' to gluten, in that symptoms worsen - like withdrawal symptoms - when they first remove it from diet - it's something to do with gluteomorphin & prodymorphin antibodies. I didn't realise how incredibly tired I still was, until I'd been gluten free for 5 weeks - Debilitating tiredness is one of the many signs that I have been 'glutened' now - I have become extremely sensitive to the minutest amounts, including the so called safe limits allowed by the Coeliac society (up to 20 parts per million). I did not want to have to go gluten free, but I feel SO much better, including not feeling anxious all the time (had high cortisol when consuming gluten). I refused to go back on gluten for official NHS diagnosis, because I couldn't bear to suffer the consequences (never mind the actual harm - my neurones were under attack!)

Was severely deficient of D3, so take 2,500 iu every 2 or 3 days along with K2 MK-7.

Am vegan so take Hydrox-Adeno B12 and B-Minus complex (dare not take methylcobalamin B12 because I have mercury amalgam fillings and don't want to 'methylate' the mercury).

Also take good quality algal Omega 3

Sometimes take zinc, selenium, calcium+magnesium, but can't always afford the supplements so stick to ones mentioned above as priorities.

Final note: If you have to avoid gluten, take care to ensure gluten-free supplements (and toothpaste etc).

Well, you did ask! :-D

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