Adjusting T3/T4 dose: Hello allA few months ago a... - Thyroid UK

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Adjusting T3/T4 dose

Molly161018 profile image
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Hello allA few months ago a member commented that I could well not be taking the optimal ratio of T4/T3 to feel my best...(I can't find this comment now so not sure who it was from)

But I was hoping for some advice how I go about tweaking this to find out what's best for me?

- how often would you test when adjusting doses?

- how long between dose changes?

- presumably you'd change one thing at a time, eg. Drop t4 dose for X weeks, then if this results in feeling worse you'd raise the t3 and so on?!

I'm currently on 125mcg T4 and 12.5mcg T3.

Thanks in advance x

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Molly161018
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pennyannie profile image
pennyannie

Hello Molly :

You need to go to your Profile Page to find everything you have ever written and all your replies to previous questions/posts,

Press the icon top right on this screen - which says - More :

Follow link to your profile page - and you should then be able to see your full history.

Jaydee1507 profile image
Jaydee1507Administrator

Testing would be every 6-8 weeks and thats how often you would change dose. It cn even take longer for a dose to 'settle' and blood results to fully adjust.

Change one thing at a time. Usually dropping a small amount of Levo, retest then add small amount of T3.

What were your latest bloods?

Have you recently had vitamins tested? What were the results? Vitamins need to be OPTIMAL for the body to be able to use the thyroid hormone well.

Molly161018 profile image
Molly161018 in reply toJaydee1507

Sorry for the delay in responding to your helpful adviceIt's two months since my last blood test, so maybe I should do another one before changing anything?

Yes I've been working at getting my vitamins optimal for a while now, and I think we're getting there, but a test will tell us I guess!

I'm currently on 125mcg t4 and 12.5mcg t3 - would you go down to 100 t4, then after 6 weeks and another test increase t3 by 6.25mcg?? Not sure whether that's small enough increments?

Jaydee1507 profile image
Jaydee1507Administrator in reply toMolly161018

You need to get an accurate blood result so stop Levo 24hrs before test, T3 split dose day before and take last dose 8-12 hours before test.

We don't know if you need to reduce Levo without seeing latest blood results. Approx 5mcgs would be the suggested dose increase.

Molly161018 profile image
Molly161018 in reply toJaydee1507

Ok, my t3 comes in 25mcg tabs, so by the time you've split it into 4 and lost a few crumbs I'm guessing each bit would be appx 5mcg 🤔

I'll do a blood test next week and go from there. Thank u for your help 🙂

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