I have central hypothyroidism. I have tried T4 only (failed) , T3 only ( better but too difficult to follow multiple doses) and also tried t4 +t3 ( 50:50 mcg as well as 50:10 mcg ) . I felt my best on 50:50 mcg dose of t4+t3 but still not 100%. So I tried 100 mcg t3 with 12.5 mcg t4. This is what i feel best on but only question I have is that I haven't found single person following a high t3:t4 protocol and hence I call upon the fellow members if it is safe to adhere to such protocol in long run !
Thanks you
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Tansin22
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I plan to draw blood after 4 weeks but I am expecting my T3 would be up in the sky anyway. Also , due to central hypothyroidism, I can't rely on my TSH.But my journey throughout has made me rely more on stmptoms rather than lab value, so was just concerned about long term effects.
I also had a question to community about proximity temperature. So my toe fingers and knees are often colder than other body parts esp at night . Should I be patient with the process or just up my dose ?
We are with you on often ignoring TSH, I'm not sure that any one thinks having long term above range fT3 or 4 is going to do anyone any good... what were your last results like?
Cold fingers and toes could be Raynard's Syndrome? Have you ever check your thyroid antibody levels could it also be under autoimmune attack?
Yes I have been a lurker on this forum for quite a bit so I have taken due cognizance to check on the basics . Tested for all autoimmunity parameters and negative
The reason why ask about long term consequences of high T3 is because most people will have palpitations at that dose but mine is just 85 bpm. Also I feel undermedicated due to the fact that my bp is still high (150/90) and I have muscle weakness (but that can be sign of overmedicated as well) . Super confused It's definitely not raynaud's as my colour of toe fingers doesn't change . Also my cortisol is normal, so pretty sure it's not raynaud's .
Would be good if you filled in your Bio as we don't have much to go on, 85bpm is a reasonably quick tick over compared to many of us, before adding T3 I was low 50's and now low 60's but BP remains low.
Muscle weakness could be low Vit D, folate, B12, iron, potassium, magnesium, calcium.... sex hormones? How are they all looking? You'll know we work on results with ranges
Ah ha, I now see you are a 33 year old, tall, slim chap.... so 85bpm seems fast unless you just aren't very fit?
What about vitamin D, folate, B12 and ferritin levels
What vitamin supplements are you taking
Recommended that all thyroid blood tests early morning, ideally just before 9am, only drink water between waking and test and last dose levothyroxine 24 hours before test
This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip)
On T3 - day before test split T3 as 2 or 3 smaller doses spread through the day with last dose 8-12 hours before test
Very good experience to share regarding levothyroxine brand .When I was on T4 solo, I started with GSK eltroxin. This improved my energy but not joint pain. After few months, due to supply issues, I switched to Euthyrox and it made my life hell. Whatever improvement I made, was gone . At that time I didn't know that levothyroxine preparations can vary with brands .
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