Weak Legs (caused by medication fillers?)

[KillashandraRee]

Just wondering if anyone else has experienced the above? I did take Teva Levothyroxine some years ago and had to change to another brand and it was all fine after changing. Have been taking Thybon Henning for 2 years (Liothyronine) and, whilst not as bad symptom wise, I now cannot walk more than 3 miles (used to do 10 - 15 mile hikes!) without knees and hip joints being quite painful, especially on the down hill. The soreness lasts days too. I had put it down to age (53), but as I am quite fit and do strength training also, decided it can't be that! I've asked private Endo for another brand of T3 so will try that, but just wondered if it was just me! Thanks all.

[Jaydee1507 Administrator]

what were your latest vitamin results?

Thybon is lactose free at least. What ingredient do you suspect in it?

Maybe need a dose adjustment?

[KillashandraRee in reply to Jaydee1507]

Thanks for your response. Vitamin levels were not done last time, however I take Selenium, D3, K2, Folate, Omega 3, Vit C and Zinc etc. every day now. Will see how it goes...

[Pearlteapot]

I take Thybon Henning and don’t have this issue. Not that that means anything since we are all different. Have you tested for rheumatoid arthritis? Or could it be something as simple as needing to stretch more? Tight hips from desk work will hurt after a long walk.

[KillashandraRee in reply to Pearlteapot]

Thank you for response. I've attached a bone profile to SlowDragon's response which doc says hasn't flagged anything up, but maybe someone will see more.

[Pearlteapot in reply to KillashandraRee]

do you take statins?

[KillashandraRee in reply to Pearlteapot]

No I don't not on any other meds apart from T4/T3 and supps

[FancyPants54]

Your age... Are you on HRT? If not, it's probably time to try it. Loss of oestrogen causes all sorts of joint and muscle problems as everything dries out and shrivels up. Oestrogen can make a world of difference.

[KillashandraRee in reply to FancyPants54]

LOL, thanks for response, yes am on HRT and have been for years. In fact changing from combined to continuous in a few weeks with a drop from 2mg to 1mg of Oestrogen so that is something to watch out for!

[FancyPants54 in reply to KillashandraRee]

Yes, definitely watch for that if going down in dose like that. I keep my oestrogen level quite high.

[SlowDragon Administrator]

Previous post showed likely under medicated

healthunlocked.com/thyroidu...

You need TSH, Ft4 and Ft3 tested

Last dose levothyroxine 24 hours before test

Last 5mcg dose T3 Approx 8-12 hours before test

Plus all four vitamins

[KillashandraRee in reply to SlowDragon]

Thanks for response SlowDragon. Last results in Dec 22 were as follows, this was with the reduction of 5mcg T3 per day. I have since gone back up to x3 5mcg T3 per day and endo is happy with TSH now it seems after seeing a slight rise in TSH (no idea why?) I have an NHS Endo appointment next week so will see how that goes and I have been in touch with lab and they quoted me £225 for compound T3 with hardly any fillers (for 3 months) which I can't quite afford right now! Therefore am sticking with Thybon Henning for now. Dec 22 results:

Free T3 - 4.8 (3.1 - 6.8)

TSH - 0.02 (0.27 - 4.2)

Free T4 - 14 (11 - 22)

B12 - 479 (197 - 771) - since started taking B12 supp

Vit D - 81 (>51) - since started taking D3 supp (and K2!)

Folate - 8.2 (>3.9) - since started taking supp

I really need updated labs! Hopefully soon. Bone profile also below - have no clue what these figures mean etc. If you have any insight, that would be great.

Excel

[SlowDragon Administrator in reply to KillashandraRee]

was this test early morning and last dose levothyroxine 24 hours before test

Last 5mcg T3 Approx 8-12 hours before test

FT4: 14 pmol/l (Range 11 - 22)

Ft4 only 27.27% through range

FT3: 4.8 pmol/l (Range 3.1 - 6.8)

Ft3 only 45.95% through range

You look a little under medicated

Many people on levothyroxine plus small dose T3 find they need both Ft4 and Ft3 at least 50-60% through range

How much levothyroxine are you taking

Suggest you try increasing levothyroxine by 12.5mcg every day. Retest in 6-8 weeks

Increase in levothyroxine should improve Ft3 a little too

Do you always get same brand levothyroxine

[KillashandraRee in reply to SlowDragon]

Yes taken early morning last dose T4 24 hours and last dose T3 over 12 hours before. I have upped T3 dose since this test so hoping next one will show better results. Currently take x3 5mcg T3, split through the day and 75mcg Levo per day. Always have same brand due to past problems. Thanks SlowDragon Should I still increase Levo as you suggested? Happy to try this to see if symptoms resolve

[SlowDragon Administrator in reply to KillashandraRee]

I would wait and see what next test shows 6-8 weeks after increasing T3

Obviously Ft4 unlikely to have increased

Which brand levothyroxine are you using