How long to wait for t3 to leave for test? - Thyroid UK

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How long to wait for t3 to leave for test?

ratqueenxo profile image
5 Replies

Hello,

I am due for a thyroid test soon after having very low T3, my endo was dubious of my hashimotos diagnoses by a functional doctor(I am however not).

I was taking T3 for around 3-4 weeks, only 10mg of a 25 mg dose (thybon henning).

I've been off it only for around 10 days, he said I could get retested after 10 days being off of it.

Is this accurate or should I wait longer? I want an authentic reading as possible since I will probably have to convince him I'm sick.

My t3 was MINUS 2.3 so I'm not sure why he didn't raise medication questions, but I'll see when I get there.

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ratqueenxo
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tattybogle profile image
tattybogle

10 days should in theory be long enough for the added T3 to have left your system. But that does not mean it's long enough for your TSH / fT4 /fT3 results to revert to their 'natural' state .

TSH can often take a few weeks (at least) to settle back to it's normal .. and as TSH changes , it affects the thyroid's production of T4 and T3 .. and it also affects the conversion of T4 to T3 in the body. So definitely the TSH and possibly the fT4 /fT3 results could all be expected to continue changing for a lot longer than 10 days .

As long as this is borne in mind there is no reason you can't test @10 days .. but if those result don't get you what you want ,, then insist on retesting after 6-8 weeks.

ratqueenxo profile image
ratqueenxo in reply to tattybogle

Awesome, thank you so much! :)

Kapuna profile image
Kapuna

I was told that T4 stays in your system but T3 doesn’t last more than a half a day so am/pm dosage works better than a single daily dose.

tattybogle profile image
tattybogle in reply to Kapuna

Not quite .. T4 has a half life of about 7 days in blood .

T3 has a half life of about 1 or 2 days in blood. (can't remember exact time off top of my head) this means after 1 or 2 days 'half of what you took has gone' (less any you used) . after another 1 or 2 days 'half of that remaining half has gone' (less any that you used)

But once within the cells . T3 continues to have it's action for 2 or 3 days . Hence some poeple are fine taking it in one daily dose . The reason for split dosing of T3 is to smooth out the effect for those that feel it , not everyone does and to moderate the highish fT3 levels in blood that happen when a full daily dose is absorbed from the gut all in one go.

shaws profile image
shawsAdministrator in reply to Kapuna

I follow a scientist/researcher/doctor who took T3 himself and he advised taking one daily dose of T3 with a glass of water that saturated all of the T3 receptor cells and stated that the effect of that one dose can last up to three days.

DrLowe is now a deceased scientist (due to an accident). His name was Dr John Lowe, who was also an Adviser to TUK (thyroiduk).

I trialled that myself by taking my usual one daily dose of T3 and toook none on day 2 or day 3 and, yes the one dose lasted three days.

The following link may be helpful:-

tpauk.com/main/article/dr-j...

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