This paper is not directly addressing T4 and T3 metabolism in subjects but is assessing linkages between the various reactions and products. It concludes that as regards pharmacokinetics of change, we are all individual in our actions, and of course leading on to individuality of response to T4 treatment. Perhaps a little esoteric, but the message is important. Downloable.
Changes in Thyroid Metabolites after Liothyronine Administration: A Secondary Analysis of Two Clinical Trials That Incorporated Pharmacokinetic Data
May 2022 Metabolites 12(6):476
DOI: 10.3390/metabo12060476
Nour DiabSameer, Desale Mark Danielsen, Jacqueline Jonklaas
The thyroid doesn't secrete 20% T3 and 80% T4, (according to the individual data from Pilo's 1990 study) - this was an AVERAGE.
Blood tests 3 weeks after decrease in both t4 and t3?
What usually happens to TSH and T# levels once a person starts taking T3 along with the T4?
