I’ve made quite a few small changes and got myself in a pickle ….
Starting point - 100mcg T4 and 15mcg T3.
I suddenly had an energy crash that lasted for days and a low T4 result hence my changes below :
21/04/22 - started 112.5mcg T4 + 15mcg T3
(2weeks)
04/05/22 - started 118.7mcg T4 + 15mcg T3
(3 days)
07/05/22 - started 125mcg T4 + 15mcg T3
(2weeks) feeling my low brain cognition still not shifting so ….
25/05/22 - started 125mcg T4 + 16.25mcg T3 (5 days)
30/05/22 - now I feel uncomfortably over medicated with shakes and internal agitation.
So, now I’m going to stop the extra 1.25mcg T3. I’m so surprised it’s been so impactful.
How long might that take to come out of my system?
I’m really anxious about feeling like this. I know I shouldn’t have made so many little changes, and that my patience needs taming.
My T4 overall increase of 25mcg was across 5 weeks and I thought that was a regular increment and had quite a long time to bed in and I had thought the T3 increase of 1.25mcg (a 5mcg tablet in quarters) was a tiny.
It wasn’t until I added the extra T3 in that my brain started working again, and before that I had to reduce my T3 because my heart didn’t like it. I’m so lost as to where the balance is.
Does anyone think a change of brand might make a difference?
(now my 15mcg T3 is Mercury Pharma and the 1.25mcg T3 is Mornington).
Written by
hobbycat
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Changing brand of levothyroxine or T3 can cause differences
How long since you started HRT …..is it tablets or topical on skin
What were most recent TSH, Ft4 and Ft3 results
Do you split your T3 as 2 or 3 smaller doses spread through the day
If your very sensitive to dose change in levothyroxine or T3 it’s best to go slowly …..just one increase in levothyroxine to 112.5mcg daily and wait 6-8 weeks before retesting
However you probably don’t want to get even more confused by reducing from 125mcg to 112.5mcg unless you have to
Is levothyroxine all the same brand
Have you considered also splitting your levothyroxine into 2 or 3 smaller doses, taking at same time as T3
HRT is gel - and I change on 21/04 - same as my first increase of T4 this time around.
TSH 0.02 T4 12.5 T3 4.6 in March.
T3 10mcg at 7am and 5mcg at 2pm. I was adding additional 1.25mcg at 6pm.
I’m abroad for 5 days so can’t cut my tablets. I’m wondering if it’s best to do 100 / 125 alternative days ? Or I could take 100mcg at 7am and 25mcg at 2pm but I feel so over medicated and I feel awful 😞 so I wonder if I should reduce ?
No I don't think it is the brand. I think it is your tinkering. As you said yourself you've made too many changes. It is frustrating but you must only change 1 thing at a time and then wait for 8 weeks for the impact of that change to show.There is no quick fix otherwise you just get in a muddle.
It took me 2 years of small changes to get to results and doses that I was happy with longer-term. It's the only way unfortunately. I had to give up my job and was housebound because of it. Only now beginning to get any life back.
We don't actually know what the current fT4 level is. I think that fT4 '12' result was from March when hobbycat was taking 100mcg levo , and it looks like levo dose has been increased to 125mcg since then .
Also, we don't have the lab range for that fT4 test, but even though [12-22] ish is a common range , some fT4 tests use ranges of eg [7 -14]... and if this test was one of those, then a result of 12 isn't low.
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Dose changes advice please 
More bl**dy questions 
