propranolol and hypothyroid : Has anyone heard... - Thyroid UK

Thyroid UK

125,613 members147,189 posts

propranolol and hypothyroid

WeeB profile image

Has anyone heard that propranolol could reduce my thyroid activity? the Gp seems to think it only reduces the symptoms of hyper thyroid , however i found some articles that say it actually reduces t3 and rt3 conversion . all the articles were a bit too scientific for me so i discussed with gp and he said he had never heard that before . i’ve came off propranolol just in case because i’m hashimotos hypothyroid but i think propranolol could have been good for me as having lots of headaches and anxiety . however i don’t want to take anything that will mess with my thyroid activity .

13 Replies

Hi WeeBI was on Propranolol to control tremors and rapid heart rate caused by Graves Disease. My GP kept me on it way longer than I should have been after my Thyroidectomy and it caused me a lot of problems including depression, fatigue, extreme paranoia and a very bad case of dry eye syndrome.

I've also read that it can affect T4 conversion which is what prompted me to take matters into my own hands and wean myself off it a couple of months ago.

I feel much better now and my eyes are almost back to normal but I do suspect it contributed to some of my weight gain too.

WeeB profile image
WeeB in reply to Helen161

Thanks for your reply , i have no idea what’s going on with me at the moment. I have a strange constant headache, eye pain , dizzyness and ear pressure. i’m hoping it’s something like a sinus issue or ear infection rather than thyroid related as headaches are not something i normally suffer from. waiting on more bloods tests now and getting treated for potential sinus stuff and also been given a new daily drug in place of propranolol to try to tackle the headaches .

WeeB profile image
WeeB in reply to WeeB

oh and numbness on right hand side of my face

Propranolol is chosen in conjunction with anti thyroid medication as its known to have a mild anti thyroid affect and can lower FT3. This is due to reprioritising the conversion of T4 to RT3 over T3, so it helpful for hyperthyroid (not for hypothyroid).

I had to resume propranolol after specialist instructed me to stop it. Never stop it abruptly, it made me quite unwell with migraines. I still take a low dose now for migraine prevention.

Can your GP recommend a beta blocker or alternative which doesn’t affect levels?

i only took one tablet before stopping and symptoms have stayed the same before and after so should be ok from withdrawal point of view . they have given me something else so hopefully it helps

Have you considered having more alkaline foods in your diet to combat the autoimmune aspect of hashimotos? Even just having a smoothie made from cucumber and melon may help

SlowDragon profile image

How much levothyroxine are you currently taking How long on this dose

What were most recent thyroid results?

Bloods should be retested 6-8 weeks after each dose change or brand change in levothyroxine

For full Thyroid evaluation you need TSH, FT4 and FT3 plus both TPO and TG thyroid antibodies tested.

Also EXTREMELY important to test vitamin D, folate, ferritin and B12

Low vitamin levels are extremely common, especially with autoimmune thyroid disease (Hashimoto’s or Ord’s thyroiditis)

Do you have Hashimoto’s

Recommended on here that all thyroid blood tests should ideally be done as early as possible in morning and before eating or drinking anything other than water .

Last dose of Levothyroxine 24 hours prior to blood test. (taking delayed dose immediately after blood draw).

This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip)

Is this how you do your tests?

Private tests are available as NHS currently rarely tests Ft3 or all relevant vitamins

List of private testing options

Medichecks Thyroid plus antibodies and vitamins

Blue Horizon Thyroid Premium Gold includes antibodies, cortisol and vitamins by DIY fingerprick test

If you can get GP to test vitamins and antibodies then cheapest option for just TSH, FT4 and FT3

£29 (via NHS private service ) and 10% off down to £26.10 if go on thyroid uk for code

NHS easy postal kit vitamin D test £29 via

WeeB profile image
WeeB in reply to SlowDragon


Thank you for this . my only recent measurement is june 2021 tsh 1.27 and i’ve been on 125mg for just under a year. i’m getting more blood tests on nhs on friday but probably just tsh again. my folate was very low in may and will be looking for those results from friday too to see if the supplements have helped .

After reading your profile it’s clear i need to get some private tests to see where i am at . Thanks for all the links . i’m curious about the gene test and the test that showed you had gluten intolerance, do you have any recommendations where i can get those two tests done ?

historicallly i have had major deficiency issues with vitamin d , b12 and folate but been on daily supplements for all for over 4 years . the folate is the only one the nhs take me off and then my levels drop and i have to go back on. in hindsight i need to be better at continuing the folate myself regardless of what my gp says rather than letting it drop. i haven’t been good with supplementing all the other things like selenium or magnesium because i find it hard to find multivitamins without iron ( i have iron overload - haemachromatisis) but again after reading your profile i think i need to be better at this and buy them individually

i’ve had a cortisol test and coeliac test done about 2-3 yrs ago and they came back fine.

SlowDragon profile image
SlowDragonAdministrator in reply to WeeB

I was astonished to find out I was gluten intolerant. If you have had negative coeliac blood test then the next step is just to try strictly gluten free diet

But wait to do this

We only want to change one thing at a time.

So first step is get full blood test, see what thyroid and vitamin levels are like

I was taking propranolol and was advised by endo to change to another beta blocker. I'm on liothyronine only and it seems propranolol interferes with its absorption. Now taking bisoprolol beta blocker . I would say it's just as good. No adverse effects or anything

My doctors found I was allergic to this medication I had a overactive thyroid but I had radiation treatment + I am now under active

I'm hypothyroid, but I do take beta blockers (BBs), specifically bisoprolol at a dose of 2.5mcg per pill - I used to cut them in half but I do need a whole pill nowadays. I take them as rarely as possible, and take them as needed for tachycardia (fast heart rate).

A few weeks ago I switched taking my thyroid hormones from morning to evening. In the process it has reduced my need for bisoprolol a lot. I've hardly taken it in the last 3 - 4 weeks.

I am aware that beta blockers reduce conversion of T4 to T3. But living with a heart rate of 120 - 150 bpm for any length of time at all is so unpleasant that I'll just take the BBs and to hell with the consequences for my thyroid hormone levels.

well I was first put on propanolol for my overactive thyroid as well as carbimazolei eventually came off the beta blocker and remained on carbimazole as I do today for 20 years plus

i am back on propanolol to settle my anxiety

in short I was originally put on propanolol because my heart was racing due to the then undiagnosed over active thyroid

You may also like...