Thyroid Peroxidase Antibodies (TPO) - Final - 14/06/2021 16:01
Thyroid Peroxidase (TPO) Abs <9 IU/ml 0 - 34
I am on 75mg levo. but so relief in my symptoms and my water retention is crazy such heavy legs and crackling in my breathing. Depression, tiredness has not improved I have been on meds for two months. Would love your views on my results. I wanted to know if anyone has had bad water retention. I also was advised by a work colleague that it might actually be my liver not working that is causing my thyroid, adrenals not to work properly?
thanking you all so much as always for your help, support and advice.
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Saintrockz
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The aim is to increase dose levothyroxine slowly upwards in 25mcg steps until TSH is ALWAYS below 2.
Most people when adequately treated will have TSH well under one
Ft4 should be near top of range and Ft3 at least 50-60% through range
Currently Ft4 is right at bottom of range
Which brand of levothyroxine are you currently taking
Request 25mcg dose increase in levothyroxine and bloods retested 6-8 weeks later
All thyroid tests should be done as early as possible in morning before eating or drinking anything other than water and last dose levothyroxine 24 hours before test
Negative TPO antibodies doesn’t rule out autoimmune thyroid disease. There’s also Thyroglobulin antibodies…but NHS won’t test as TPO antibodies are negative
20% of Hashimoto’s patients never have high thyroid antibodies, ultrasound scan can help diagnose
Have you had ultrasound scan of thyroid
Extremely important to regularly retest vitamin D, folate, ferritin and B12
Even if we frequently don’t start on full replacement dose, most people need to increase levothyroxine dose slowly upwards in 25mcg steps (retesting 6-8 weeks after each increase) until eventually on, or near full replacement dose
Consider starting levothyroxine at a dosage of 1.6 micrograms per kilogram of body weight per day (rounded to the nearest 25 micrograms) for adults under 65 with primary hypothyroidism and no history of cardiovascular disease.
Traditionally we have tended to start patients on a low dose of levothyroxine and titrate it up over a period of months. RCT evidence suggests that for the majority of patients this is not necessary and may waste resources.
For patients aged >60y or with ischaemic heart disease, start levothyroxine at 25–50μg daily and titrate up every 3 to 6 weeks as tolerated.
For ALL other patients start at full replacement dose. For most this will equate to 1.6 μg/kg/day (approximately 100μg for a 60kg woman and 125μg for a 75kg man).
If you are starting treatment for subclinical hypothyroidism, this article advises starting at a dose close to the full treatment dose on the basis that it is difficult to assess symptom response unless a therapeutic dose has been trialled.
hey slow dragon. thank you for the quick feedback, i take mercury pharma as when i was put up to 75 mg it was the brand that had 50mg and 25mg tablets. my doctor has agreed to prescribe t3 5mg three times a day. please would you mind advising how i should take that is it at 4am? and slowly starting with 5mg and after a few days adding another 5mg and so on?
i always have my bloods in the mornign with no breakfast or tea/coffee and i am taking supplements for my vitamins and minerals.
my water rentention is very bad and dr was worried it could be heart related and not thyroid.
have you read the articles which say it is a liver problem that causes the thyroid not to work?
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