Blood results hypothyroidism

[Nattie663]

Good morning Guys, so last week I put a post about been diagnosed, i have had more results and have to wait for 1 week for a telephone consult with the doctor to discuss them and i would like to be prepared and know what i am talking about.

25th May

ESR 28mm/h range 1-12 - my ESR has always been high - no-one knows why

anti-tissue transglutnase (anti TTG) Level <1.0 kU/L range 0.00 - 10.00

Se thyroid peroxidase (TPO) 13 iu/mL range 0.00 - 34.00 <35 = negative

FSH 17.4 iu/L

LH 18.2iu/L

Range varies for different stages

combined vit D2 & D3 - 64.3 nmol/L range 50.00-150.00

serum ferritin 104 ug/L range 13.00-200.00

Previous TSH level 8 range 0.3 - 4.2

previous folate 5.9 range 3.89 - 26.8

previous B12534 range197-771

folate 5.9 range 3.89 - 26.8

cholesterol 7 range 0-5

cholesterol ratio 4.5 range 0-5

Any information would be greatly received as I'm unsure why my antibody test would be negative .

Been taking Levo for 3 weeks 50mg

thanks in advance

[greygoose]

I'm unsure why my antibody test would be negative .

Presumably because you don't have autoimmune thyroiditis (aka Hashi's). Although one negative result is not conclusive for three reasons:

a) antibodies fluctuate: a second test could be positive

b) there are two antibody tests for Hashi's: TPO and Tg antibodies: the NHS only tests for TPOab, but TgAB could also be high, indicating Hashi's.

c) 20% of Hashi's sufferers never have over-range antibodies, and are diagnosed by unltrsound of the thyroid.

Is this the first antibody test you've had?

[Nattie663 in reply to greygoose]

Yes this is the first test I’ve ever had an antibodies test.

[greygoose in reply to Nattie663]

OK, well, if the occasion arises, perhaps get it get done again sometime.

[SlowDragon Administrator]

So TSH is high

No Ft4 or Ft3

Bloods should be retested 6-8 weeks after each dose change or brand change in levothyroxine

Which brand of levothyroxine are you currently taking

Dose levothyroxine should be increased slowly upwards in 25mcg steps until TSH is ALWAYS under 2 as maximum

Most important results are always Ft3, followed by Ft4.

Aiming for ideally both approx 60% through range

TPO antibodies negative

As greygoose says, NHS refuses to test TG antibodies unless TPO antibodies are positive.

Significant minority of Hashimoto’s patients only have high TG antibodies..

And 20% never have high thyroid antibodies

Perhaps consider getting full thyroid testing in few weeks privately....especially as NHS almost never test Ft3 and can even be difficult to get Ft4 tested

All thyroid tests should be done as early as possible in morning before eating or drinking anything other than water and last dose levothyroxine 24 hours before test

[SlowDragon Administrator]

High cholesterol levels will reduce as dose levothyroxine is increased over coming months

nhs.uk/conditions/statins/c...

If you have an underactive thyroid (hypothyroidism), treatment may be delayed until this problem is treated. This is because having an underactive thyroid can lead to an increased cholesterol level, and treating hypothyroidism may cause your cholesterol level to decrease, without the need for statins. Statins are also more likely to cause muscle damage in people with an underactive thyroid.

Vitamins

Ferritin is good

Vitamin D and folate need improving

What vitamin supplements are you currently taking

[Nattie663 in reply to SlowDragon]

I don’t take any supplements, what would you suggest? I just want to feel better. Exhausted, muscle aches and weakness.

I must say though I have started to sleep a bit better