I take 50mcg of Levothyroxine T4
and 5 mcg of Liothyronine T 3 cytomel in the morning empty stomach .
Has anyone tried taking T3 in the afternoon & noticed the difference? Is it better to take morning or afternoon or later ...
Been having trouble posting on the app lately !
Suzie. T3 has half life of 5-6 hours. Some people take all of their dose in the morning and are fine, some people do split their T3 into two or three doses to tale during the day. Im on a ndt and take my whole dose first thing in the morning. I used to split it and do a top up at lunchtime but since my b12 jabs no longer need to. Never tried night before......but I know some people take their levo at bedtime & feel great. Not heard of anyone doing the same with T3.
The plasma half-life of T3 is around a day!
There are some who take T3 at bed-time - whether whole dose or just one part of a split dose.
Dr Lowe apparently used to take his huge dose then.
I am on 5 mcg of T3 Liothyronine, been taking both T3 T4 in the am. my dr suggested taking T 3 in the afternoon to boost energy. I am reluctant to do that as I already have insomnia problem at least two days a week.Thanks
You could well be right. But some people sleep better by doing so!
I do not take T3, but I do take my levothyroxine at bedtime and usually sleep very soundly - which I didn't prior to treatment.
That’s nice to know.
My dr says to take Levothyroxine on empty stomach, first thing in the morning
They all say that. Just difficult to know whether it is out of ignorance or it is the easy option.
Some papers which discuss taking levothyroxine at different times - such as bed-time.
Levothyroxine Replacement and Ramadan Fasting
pubmed.ncbi.nlm.nih.gov/237...
Effect of L-Thyroxine Administration Before Breakfast vs at Bedtime on Hypothyroidism: A Meta-Analysis
pubmed.ncbi.nlm.nih.gov/320...
Morning vs. Bedtime Levothyroxine Administration: What Is the Ideal Choice for Children?
pubmed.ncbi.nlm.nih.gov/303...
A Crossover Study Evaluating Effect of Timing of Levothyroxine on Thyroid Hormone Status in Patients of Hypothyroidism
pubmed.ncbi.nlm.nih.gov/313...
Effect of Timing of Levothyroxine Administration on the Treatment of Hypothyroidism: A Three-Period Crossover Randomized Study
pubmed.ncbi.nlm.nih.gov/300...
Alternative Schedules of Levothyroxine Administration
pubmed.ncbi.nlm.nih.gov/256...
Thyroid Diseases and Ramadan
pubmed.ncbi.nlm.nih.gov/228...
Pharmacotherapy: Hypothyroidism-Should Levothyroxine Be Taken at Bedtime?
pubmed.ncbi.nlm.nih.gov/213...
Effects of Evening vs Morning Levothyroxine Intake: A Randomized Double-Blind Crossover Trial
pubmed.ncbi.nlm.nih.gov/211...
Timing of Levothyroxine Administration Affects Serum Thyrotropin Concentration
pubmed.ncbi.nlm.nih.gov/195...
Effects of Evening vs Morning Thyroxine Ingestion on Serum Thyroid Hormone Profiles in Hypothyroid Patients
When is the best time to take T3
Best time to have blood test
Time to take more T3?
Best time to take medication?
Best Time to take Vitamin D3?
