Hashimotos disease?

[georgiego]

Hi all, my mum got these results & I was wondering why she would have such high antibodies but thyroid levels in range? Does this mean she has hashimotos? She's not on any medication. I myself have graves disease but now hypo after RAI treatment. Thanks.

[greygoose]

There is no direct connection between thyroid hormone levels and antibody levels

The antibodes are high because she has Hashi's. And, and they fluctuate all the time. Usually, they are highest just after an autoimmune attack on the thyroid. But, she doesn't appear to have had a Hashi's 'hyper' swing, because her Frees are quite low, and her TSH highish. But, Hashi's antibodies do just tend to do their own thing, with no obvious rhyme or reason.

[georgiego in reply to greygoose]

Thank you Greygoose.

[greygoose in reply to georgiego]

You're welcome.

[SlowDragon Administrator]

Does she have hypothyroid symptoms

Recommend she gets vitamin D, folate, ferritin and B12 levels tested......likely very low

Her Ft4 is very low and Ft3 fairly low

Look at trialing strictly gluten free diet in new year too

Hashimoto's frequently affects the gut and leads to low stomach acid and then low vitamin levels

Low vitamin levels affect Thyroid hormone working

Poor gut function can lead leaky gut (literally holes in gut wall) this can cause food intolerances. Most common by far is gluten. Dairy is second most common.

According to Izabella Wentz the Thyroid Pharmacist approx 5% with Hashimoto's are coeliac, but over 80% find gluten free diet helps, sometimes significantly. Either due to direct gluten intolerance (no test available) or due to leaky gut and gluten causing molecular mimicry (see Amy Myers link)

Changing to a strictly gluten free diet may help reduce symptoms, help gut heal and slowly lower TPO antibodies

While still eating high gluten diet ask GP for coeliac blood test first or buy test online for under £20, just to rule it out first

healthcheckshop.co.uk/store...?

Assuming test is negative you can immediately go on strictly gluten free diet

(If test is positive you will need to remain on high gluten diet until endoscopy, maximum 6 weeks wait officially)

Trying gluten free diet for 3-6 months. If no noticeable improvement then reintroduce gluten and see if symptoms get worse

chriskresser.com/the-gluten...

amymyersmd.com/2018/04/3-re...

thyroidpharmacist.com/artic...

drknews.com/changing-your-d...

restartmed.com/hashimotos-g...

Non Coeliac Gluten sensitivity (NCGS) and autoimmune disease

ncbi.nlm.nih.gov/pubmed/296...

The predominance of Hashimoto thyroiditis represents an interesting finding, since it has been indirectly confirmed by an Italian study, showing that autoimmune thyroid disease is a risk factor for the evolution towards NCGS in a group of patients with minimal duodenal inflammation. On these bases, an autoimmune stigma in NCGS is strongly supported

ncbi.nlm.nih.gov/pubmed/300...

The obtained results suggest that the gluten-free diet may bring clinical benefits to women with autoimmune thyroid disease

nuclmed.gr/wp/wp-content/up...

In summary, whereas it is not yet clear whether a gluten free diet can prevent autoimmune diseases, it is worth mentioning that HT patients with or without CD benefit from a diet low in gluten as far as the progression and the potential disease complications are concerned

restartmed.com/hashimotos-g...

Despite the fact that 5-10% of patients have Celiac disease, in my experience and in the experience of many other physicians, at least 80% + of patients with Hashimoto's who go gluten-free notice a reduction in their symptoms almost immediately.

[georgiego in reply to SlowDragon]

She does have symptoms indeed. Has been going to the doctor for years about her symptoms...hair loss, fatigue, weight gain and bowel problems but with no help. She got her vitamins tested with medichecks tooFerritin 19.3 (13-150)

Folate 4.53 (>3.89)

B12 74.5 (>37.5 pmol/L)

Vit D 83 ( 50-175) this was after a 6week course of higher level vitD supplements.

Can the hashimotos give her hypo symptoms?

Thank you for all that info, its very interesting and worth a try.

[SlowDragon Administrator in reply to georgiego]

Ferritin far too low

Folate very low as well

Vitamin D obviously was low and now nearly optimal

[SlowDragon Administrator in reply to georgiego]

drhedberg.com/ferritin-hypo...

This is interesting because I have noticed that many patients with Hashimoto’s disease and hypothyroidism, start to feel worse when their ferritin drops below 80 and usually there is hair loss when it drops below 50.

Never supplement iron without doing full iron panel test for anaemia first

Post discussing why important to do full iron panel test

healthunlocked.com/thyroidu...

Eating iron rich foods like liver or liver pate once a week plus other red meat, pumpkin seeds and dark chocolate, plus daily orange juice or other vitamin C rich drink can help improve iron absorption

List of iron rich foods

dailyiron.net

Links about iron and ferritin

irondisorders.org/too-littl...

davidg170.sg-host.com/wp-co...

Great in-depth article on low ferritin

oatext.com/iron-deficiency-...

Thyroid disease is as much about optimising vitamins as thyroid hormones

healthunlocked.com/thyroidu...

restartmed.com/hypothyroidi...

Post discussing just how long it can take to raise low ferritin

healthunlocked.com/thyroidu...

[SlowDragon Administrator in reply to georgiego]

Low folate

supplementing a good quality daily vitamin B complex, one with folate in (not folic acid) may be beneficial.

This can help keep all B vitamins in balance and will help improve B12 levels too

Difference between folate and folic acid

chriskresser.com/folate-vs-...

Many Hashimoto’s patients have MTHFR gene variation and can have trouble processing folic acid.

thyroidpharmacist.com/artic...

B vitamins best taken after breakfast

Igennus Super B is good quality and cheap vitamin B complex. Contains folate. Full dose is two tablets per day. Many/most people may only need one tablet per day. Certainly only start on one per day (or even half tablet per day for first couple of weeks)

Or Thorne Basic B is another option that contain folate, but is large capsule

If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 7 days before ALL BLOOD TESTS , as biotin can falsely affect test results

endo.confex.com/endo/2016en...

endocrinenews.endocrine.org...

Low B12 symptoms

b12deficiency.info/signs-an...

[georgiego in reply to SlowDragon]

SlowDragon, thank you so much. Will give these all a thorough read. Appreciate your help.