Yesterday morning, I started on a new batch of T3, the packaging states they are made by Sanofi-Aventis (I’ve attached a photo). My previous batch were by SigmaPharm. By yesterday lunchtime I felt pretty unwell, it’s hard to explain how but a bit nauseous and very wiped out. I have been in bed since and when I get up, I feel like I need to sit down pretty quickly. I’m certain it’s not a bug because I’m more or less shielding and no one else in my family has been ill. So I wonder if it could be the brand of T3. Does anyone have experience of this?
Problems with T3: Yesterday morning, I started on... - Thyroid UK
Problems with T3
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Spangle15
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helvellaAdministratorThyroid UK
You surprise me there! Recently Sanofi-Aventis had manufacturing problems with their Cynomel liothyronine product. Hence there were shortages of it in France. Is that the product you have received?
We do have a few members who take Sanofi-Aventis Cynomel. Hopefully you will receive responses from some of them.
I’m not sure if it’s the same as you mention. I’ve attached a photo to my post to help.
Ah! They used to just put Sanofi Deutschland on Henning Thybon! (Or I think they did... 
)
SigmaPharm make tablets in 5, 25 and 50 micrograms. But Henning Thybon is 20 micrograms. Has your dose changed?
UK Liothyronine Tablets and Oral Solutions
➖➖➖➖➖➖➖➖➖➖➖➖➖➖
Last updated 10/10/2020.
This is a list of currently marketed liothyronine tablets in the UK.
Please note that re-branding (whether by a manufacturer or as an ‘own label supplier’) – which has happened with several products – does not mean any change to formulation.
—————————————————————
🔹 Advanz (marketing authorisation holder) – branded Mercury Pharma (also branded Tertroxin but not marketed under that brand in the UK)
🏭 Custom Pharmaceuticals Ltd. (manufacturer)
🥛 contains lactose
20 microgram PL 10972-0033
🟢 PIL mhraproducts4853.blob.core....
🟣 SPC mhraproducts4853.blob.core....
—————————————————————
🔹 Morningside (marketing authorisation holder) – branded Morningside Liothyronine and Iraksin
🏭 Morningside Pharmaceuticals Ltd. (manufacturer)
🥛 contains lactose
5 microgram PL 20117-0323
10 microgram PL 20117-0324
20 microgram PL 20117-0270
🟢 PIL Morningside Liothyronine & Iraksin 5, 10 & 20 microgram mhraproducts4853.blob.core....
🟣 SPC Morningside Liothyronine & Iraksin 5 microgram mhraproducts4853.blob.core....
🟣 SPC Morningside Liothyronine & Iraksin 10 microgram mhraproducts4853.blob.core....
🟣 SPC Morningside Liothyronine & Iraksin 20 microgram mhraproducts4853.blob.core....
—————————————————————
🔹 Teva – (marketing authorisation holder)
🏭 TEVA Gyógyszergyár Zrt. in Hungary (manufacturer)
No lactose ingredient
20 microgram PL 00289/2116
🟢 PIL mhraproducts4853.blob.core....
🟣 SPC mhraproducts4853.blob.core....
➖➖➖➖➖➖➖➖➖➖➖➖➖➖
Some non-UK Liothyronine Tablets
—————————————————————
🔹 Abdi Ibrahim (marketing authorisation holders – Turkey) – branded Tiromel
🏭 Abdi Ibrahim, Turkey (manufacturer)
🥛 contains lactose
25 microgram
—————————————————————
🔹 Ace (marketing authorisation holder – Netherlands) – branded Cytomel
🏭 Ace (manufacturer)
5 microgram
12.5 microgram
25 microgram
—————————————————————
🔹 Greenstone (marketing authorisation holder – USA) – branded Greenstone
🏭 Peptido GmbH in Germany (manufacturer)
No lactose ingredient
5 microgram NDC 59762-1206-1
25 microgram NDC 59762-1207-1
50 microgram NDC 59762-1208-1
🟢🟣 dailymed.nlm.nih.gov/dailym...
—————————————————————
🔹 Grossman Cynomel (marketing authorisation holder – Mexico)
🏭 Grossman subsidiary of Bausch (formerly Valeant) in Mexico (manufacturer)
25 microgram
—————————————————————
🔹 IBSA oral solution (marketing authorisation holder – Italy) – branded Liotir
🏭 IBSA Farmaceutici Italia S.r.l in Italy (manufacturer)
No lactose ingredient
5 microgrammi/ml
10 microgrammi/ml
15 microgrammi/ml
20 microgrammi/ml
🟢 PIL – farmaci.agenziafarmaco.gov....
—————————————————————
🔹 Mayne Pharma (marketing authorisation holder – USA) – branded Mayne Pharma (formerly Libertas, Perrigo and Paddock)
🏭 manufactured in Germany (manufacturer)
No lactose ingredient
5 microgram NDC 51862-320-01
25 microgram NDC 51862-321-01
50 microgram NDC 51862-322-01
🟢🟣 dailymed.nlm.nih.gov/dailym...
—————————————————————
🔹 Pfizer (marketing authorisation holder – USA) – branded Cytomel
🏭 Peptido GmbH manufactured in Austria and/or Germany
No lactose ingredient
5 microgram NDC 60793-115-01
25 microgram NDC 60793-116-01
50 microgram NDC 60793-117-01
🟢🟣 dailymed.nlm.nih.gov/dailym...
—————————————————————
🔹 Sanofi (marketing authorisation holder – France) – branded Cynomel
🏭 PATHEON FRANCE in France (manufacturer)
No lactose ingredient
25 microgram ANSM 34009 302 775 5 3
🟢 PIL (French) base-donnees-publique.medic...
🟣 SPC base-donnees-publique.medic...
—————————————————————
🔹 Sanofi Deutschland (marketing authorisation holder – Germany) – branded Henning Thybon
🏭 Sanofi-Aventb, Barcelona, Spain (manufacturer)
No lactose ingredient
20 microgram ZN 6085344.00.00
100 microgram ZN 6085344.01.00
🟢 PIL 20 (German) mein.sanofi.de/produkte/Thy...
🟢 PIL 20 (English translation – out of date) dropbox.com/s/ccfr0tnmr7nom...
🟢 PIL 100 (German) mein.sanofi.de/produkte/Thy...
🟣 SPC 20 & 100 (German) mein.sanofi.de/produkte/Thy...
—————————————————————
🔹 SigmaPharm (marketing authorisation holder – USA)
🏭 Sigmapharm Laboratories, LLC in USA (manufacturer)
No lactose ingredient
5 microgram NDC 42794-018-12
25 microgram NDC 42794-019-12
50 microgram NDC 42794-020-12
🟢🟣 dailymed.nlm.nih.gov/dailym...
—————————————————————
🔹 Sun Pharmaceutical Industries (marketing authorisation holder – USA)
🏭 Sun Pharmaceutical Industries Limited in USA (manufacturer)
No lactose ingredient
5 microgram NDC:62756-589-83, NDC:62756-589-88, NDC:62756-589-08, NDC:62756-589-18
25 microgram NDC:62756-590-83, NDC:62756-590-88, NDC:62756-590-08, NDC:62756-590-18
50 microgram NDC:62756-591-83, NDC:62756-591-88, NDC:62756-591-08, NDC:62756-591-18
🟢🟣 dailymed.nlm.nih.gov/dailym...
—————————————————————
🔹 Uni-Pharma (marketing authorisation holder – Greece)
🏭 Uni-Pharma in Greece (manufacturer)
25 microgram
🟢🟣
➖➖➖➖➖➖➖➖➖➖➖➖➖➖
🔹 – identifies marketing authorisation holder (or equivalent in other countries)
🔸 – identifies ‘own label supplier’ products
🏭 – identifies manufacturers (where known)
🥛 – contains lactose
🟢 PIL – Patient Information Leaflet
🟣 SPC – Summary of Product Characteristics document
🟢🟣 – Single document combining typical PIL and SPC information
—————————————————————
Numbers refer to tablet dosages in micrograms.
Only products which definitely contain lactose are identified (🥛 contains lactose). Please always check other products. Where products are ‘own label supplier’, check the marketing authorisation holder for the specific product.
If there is anything inaccurate in this information, please let me know by Private Message, or on the forum:
healthunlocked.com/user/hel...
➖➖➖➖➖➖➖➖➖➖➖➖➖➖
This document is updated whenever I am aware of any changes or enhancements are needed. Please check the Last updated date. The current version is available as a PDF here:
dropbox.com/s/xlibro9l9jbfb...
The PDF version of this document has a QR code above this sentence. If your device has a camera and can interpret QR codes, this QR code should take you to the same place as the link and make it easier to download on devices, such as phones and tablets.
No I haven’t. I’m on 10mcg. But it worked out £200 plus to buy 5 mcg and take 2 daily for 3 months, or £60 to buy 20mcg and cut them in half. Hence the change in brands, because of costing less. But it looks like the ingredients are quite different so I’m wondering if it could be that. According to Roseway who I got them from, I have taken the 20mcg brand previously though. Thank you so much for your help.
That is quite a price difference!
I hope those with experience respond soon.
Thank you. I know, it felt silly to pay that much more but now I wonder if it was the right decision.
Sigma Pharma
At £120 for 90 tablets (£1.40 per tablet)
Here’s a post I made about different prices from 11 months ago
That’s the brand I take. My endo said that it was more widely tolerated.I can react badly to some meds (can’t take generic Sumatriptan), but this Thybon Henning I’m fine with.
I take 5mcg twice a day.
Thank you. Can I ask when you last got some?
All this year. Last prescription was in October. Next prescription going to be requested in about 10 days. Not expecting any change. My 50mcg tablets from them are Accord.
Thank you. Maybe I’ll give it another few days, perhaps it’s just a coincidence I feel unwell.
Sorry, thought I was replying to another post 🤪I last received Thybon from Germany in September.
(You must have wondered what the heck Accord 50 was)
I’ve been on the same brand of T3 for 3 years.
Do you split your dose? If you don’t, it might be worth trying that.
No I don’t anymore. The logistics of supplements and eating and other meds make it difficult. I’ve basically gone from taking 2 x 5mcg in the morning to half of 20mcg so I’ve not changed doseage, just brand.
It’s all rather complicated isn’t it? I know my husband sometimes rolls his eyes at my routines. I have to do it all just right or I get all messed up and feel rough. I hope it calms down for you and you can tolerate the new tablets. 🙂
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