Pill formulation for T4 and T3

[diogenes]

This short commentary is open file and of interest in that it discusses relations between the particular formation and patient acceptance.

Thyroid

New Formulations of Levothyroxine in the Treatment of Hypothyroidism: Trick or Treat?

Endre V. Nagy, Petros Perros, Enrico Papini, Monika Katko, and Laszlo Hegedüs

Published Online:2 Nov 2020doi.org/10.1089/thy.2020.0515

[UrsaP]

linda96

[shaws Administrator]

They may be beneficial for some people and thanks for posting diogenes.

Levothyroxine did me no favours as it made me far more unwell than before I diagnosed myself 2 two hours after GP told me there was nothing wrong.

(TSH 100).

[vocalEK in reply to shaws]

What? Did your GP know the TSH was 100? If he did know and still told you there is nothing wrong, he's a mal-practitioner.

[shaws Administrator in reply to vocalEK]

My answer is 'yes'. I also at that time had no clue about hypothyroidism. Believe me, like many others on the forum we expect doctors to be knowledgeable but found that they do not have an incling.

What about the following call from another GP after a blood test:

Mrs ? your TSH is too low: your T3 is too high and T4 too low.

Me: Yes, doctor that's because I don't take levothyroxine (T4) but liothyronine (T3).

Doctor: "But T3 converts to T4".

Me: I'm sorry doctor it's the other way around. T4 converts to T3.

You can click on my name if you want a full history.

[vocalEK in reply to shaws]

Wow! Just wow!

[humanbean]

Although I'm all in favour of patients being given as many choices of medication types as possible, there is one thing you can do with a tablet that you can't do with a softgel.

Tablets can be cut and can be used to fine tune medications to a dose that helps the patients feel at their best.

[helvella Administrator Thyroid UK in reply to humanbean]

Though Tirosint gel caps come in dosages as low as 13 micrograms (obviously, 12.5 micrograms rounded up!)

The problem then becomes one of cost - with Tirosint already being expensive, imagine needing 100 alternating with 113. That would increase cost by 50% compared with 100 or 112 every day. Whether you approach it by taking 100 every day plus 13 every other day. Or 100 alternating with 112.

Link to dosages available: tirosint.com/what-makes-tir...

[helvella Administrator Thyroid UK in reply to helvella]

Of course, that is rubbish. Alternating 100 and 112 is no more expensive. But 100 alternating with 100+13 is 50% more expensive.

[Gigi216]

Yes on synthroid alone I get edema in legs and chest pain. I always need some porcine thyroid to feel my best