Thyroid Dose: Does maintaining a thyroid starting... - Thyroid UK

Thyroid UK

141,245 members166,488 posts

Thyroid Dose

jconnor123 profile image
34 Replies

Does maintaining a thyroid starting dose of 1 grain for 5-6 weeks risk worsening someones hypothyroid symptoms? I have seen this said but I'm not sure if it's a myth or not. I want to maintain this starting dose of Tru Thyroid for just over a month, then after that add 1/4th or 1/2 grain on every two weeks. This makes sense to me, however, I thought it would be worth checking as I am fairly new to thyroid supplementation

Thanks, Connor

Written by
jconnor123 profile image
jconnor123
To view profiles and participate in discussions please or .
Read more about...
34 Replies
Lalatoot profile image
Lalatoot

The starting dose is usually a quarter or half a grain. Starting on one grain is too much in my opinion.

greygoose profile image
greygoose

I take it you're already on 1 grain, and that was your starting dose?

What often happens is that when you first start taking thyroid hormone, whatever it might be, your body welcomes the extra hormone after not having much for a while, and you feel better. But then it becomes obvious that it's not enough, so your symptoms start to creep back in again. All it means is that you're ready for an increase in dose. It doesn't mean that it's worsened your symptoms.

Why do you want to stay on that dose for a month if your symptoms have returned? It doesn't make a medical sense. Or are you wanting to retest before increasing? If so, you'd have to be on it for six weeks.

People usually start with 1/4 grain, then increase by 1/4 grain every two weeks. And, when they reach 1 whole grain, hold for six weeks and retest. Then increase further if necessary - but only by 1/4 grain every two weeks. If you increase by 1/2 grain every time, you risk missing your sweet-spot. It's easily done if you increase too fast.

jconnor123 profile image
jconnor123 in reply togreygoose

Yes I want to test my blood after being on one grain for awhile to see where my bloods were at; but I've just been a little cautious about waiting so long as per recommendations here with what I was saying in op. I've been on one grain for close to two weeks thus far, I'm not sure if that was a bad dose to start off on but I thought that was the recommended starting dose

greygoose profile image
greygoose in reply tojconnor123

Well, it's not recommended on here. But, depends, were you taking something else before NDT?

Even so, not much point in testing before six weeks on the same dose. You won't get the full effects until at least six weeks.

But, going back to your original question, staying on your starting dose of 1 grain for one month will not do you any harm, it's whether or not you can put up with the returning symptoms. :)

jconnor123 profile image
jconnor123 in reply togreygoose

Nope I have been on NDT only. Like you say, I'll do my best to stick on 1 grain for as close to 6wks as possible then retest. Hopefully the long stretch being on one grain compensates for starting on one grain instead of half a grain

greygoose profile image
greygoose in reply tojconnor123

Well, if you haven't felt any ill effects so far, then it should be fine. :)

HMBradley53 profile image
HMBradley53 in reply tojconnor123

I cut my dose in half and take them 12 hours apart at the advise of my Dr because taking the full dose at once was too much. He was right taking the half dose twice a day was a game changer for me I felt so much better. I take 1 grain at 2am before work and 2pm... Cut it in half and see how you feel

jconnor123 profile image
jconnor123 in reply toHMBradley53

Yeah might try that myself. Have you not eaten for a few hours when you take your second dose at 2pm or do you take it with food?

HMBradley53 profile image
HMBradley53 in reply tojconnor123

No food my 2am dose is before work and by the time I get there and make a coffee it's 3am and my 2pm dose I have nothing but water from 1pm take my dose at 2pm and nothing 3pm accept water.

jconnor123 profile image
jconnor123 in reply togreygoose

I will definitely break my tablets in half and go for the 1/4 increments I think when I next up it.

greygoose profile image
greygoose in reply tojconnor123

That would be best, yes. :)

jconnor123 profile image
jconnor123 in reply togreygoose

Does thyroid correct high cortisol by the way? I got my saliva cortisol results back today and can see that my noon cortisol is high but the rest are in normal range

greygoose profile image
greygoose in reply tojconnor123

No, it doesn't really work like that. But, it may help your adrenals to regulate the daily out-put of cortisol, so that it's highest first thing in the morning, and gradually drops throughout the day so that it's at its lowest at bedtime.

Difficult to say without seeing all your results and ranges, but your noon cortisol is probably high because your early morning cortisol is too low - even though it's in range. The adrenals will continue trying to produce their daily quota, despite the time of day, so that levels become inappropriately high later in the day. Once the early morning cortisol is at optimal level, other levels during the day will drop back into place.

jconnor123 profile image
jconnor123 in reply togreygoose

These are the results + ranges

i.imgur.com/Nuw7JTz.png

greygoose profile image
greygoose in reply tojconnor123

Yes, your early morning cortisol is quite low in range. But, a little TLC should help that: plenty of B vits and vit C, plenty of salt, a high protein breakfast first thing (take your NDT later) and plenty of rest, and, of course, raising your T3, should help raise your early morning cortisol, so the noon cortisol will drop.

jconnor123 profile image
jconnor123 in reply togreygoose

Yeah I'll try that. I usually leave breakfast till late and usually have fruit when I first wake up so would be worth a go. Do you reckon splitting the NDT dose in half twice a day could help as well as someone below suggested?

greygoose profile image
greygoose in reply tojconnor123

Splitting the dose helps some people. Taking it all in one go suits others. You'd have to try it to find out if it helps you. :)

jconnor123 profile image
jconnor123 in reply togreygoose

i will do thanks a lot

greygoose profile image
greygoose in reply tojconnor123

You're welcome. :)

Lora7again profile image
Lora7again

How are you feeling? I got up to 1 1/2 grains of Thyroid S but I am smaller than you being a woman so you probably need an increase. As I have said before if you increase by 1/4 grain and you feel jittery you can always reduce it and try again in a couple of weeks. Just to add I never had a blood test just went by how I felt because I knew the blood test would show a suppressed TSH and a low T4.

jconnor123 profile image
jconnor123 in reply toLora7again

Really good these past couple of days. This NDT from Thailand is working better than any I've tried in the past. Im about 190 lbs so I'll see how i do on 1/4 grain increases.

Lora7again profile image
Lora7again in reply tojconnor123

I'm pleased to hear that, as I said before you go by how you feel with NDT and I didn't do any blood tests but you might want to so you see what your levels are now compared to what they were before.

JAmanda profile image
JAmanda

Are you self medicating?

jconnor123 profile image
jconnor123 in reply toJAmanda

I am yeah

JAmanda profile image
JAmanda in reply tojconnor123

Based on what test results? I think people would like to see your tsh, T3, t4 and the ranges prior to you medicating to see what might work. And why start with what I guess is ndt? You’re very brave!

Lora7again profile image
Lora7again in reply toJAmanda

NDT is very natural and was used years before the artificial Levothyroxine. In those days there were no blood tests and people went by how they felt

JAmanda profile image
JAmanda in reply toLora7again

It’s natural but really strong - I’d be very apprehensive of trying it without testing blood levels first. Even then I’m not sure I’d start with a whole grain.

Lora7again profile image
Lora7again in reply toJAmanda

I felt really well on it and yes it is strong but you can adjust the dose easily because it contains T3. I started on a 1/4 grain and slowly worked myself up to 1 1/2 grains. I am not taking it at the moment but I still have some and I would not hesitate to take it again if my levels become too low. Also your TSH will become very low or suppressed when you take it and your T4 will become lower. It doesn't suit everyone but a lot of members take it and it has helped them recover their health.

JAmanda profile image
JAmanda in reply toLora7again

Well I’m confused by your confusion then! If it were me I’d do blood tests, see where I’m at, self medicate, then retest after 6 weeks. You’ve got no baseline to compare how you feel with what your blood is like. Forgive me if I’ve missed something above and misunderstood but I’d want a lot more info - vitamins too - before self prescribing.

Lora7again profile image
Lora7again in reply toJAmanda

If you look on my profile and scroll down you will see my results from earlier this year. As I said I am taking nothing at the moment because I don't need it. I have actually just filled in a form so I can look at my Endocrinologist's records about me when he told me I had Graves' disease 10 years ago. At that time I didn't know anything about my condition which of course has changed now because I have been reading lots about thyroid disease since then. I do intend to have another blood test once the coronavirus is under control. The last thing I want to do is to go my local hospital to have my blood drawn because at the moment I don't feel safe visiting it. Having said that I just had my hair dyed yesterday and I did actually feel safe because it is a small salon and only a couple of customers were there at the same time. I did get a very sweaty face because I was wearing a mask for 2 hours but it wasn't as bad as I thought.

jconnor123 profile image
jconnor123 in reply toJAmanda

Yeah I will be doing a blood test each time before increasing my dose; however, it's quite safe if the dose is increased slowly, and the basal temps, pulse and symptoms are kept an eye on I think.

carolcw profile image
carolcw

Hi Connor, how are you doing on Tru? I received the NDT powder (Not defatted unlike the NDT tablet form like Tru etc) from same supplier - took 3 months to get here- and am trialling it now. I know the Tru tablets are 2 tablets are equivalent to 1 grain of other NDTs (like Thyroid S, Armour) and see you started at 1 Tru tablet which would be 1/2 grain of Armour equivalent. I don’t need a lot of ndt anymore (c less than 1 grain outside of winter) and was wondering about the Tru tablets. I think the powder is ok but it may suit someone who takes several grains a day as 1/4 tsp is c3 grains of NDT.

jconnor123 profile image
jconnor123 in reply tocarolcw

I have noticed more of an effect these past few days since multi-dosing, but my waking temperatures are still low and I still have low thyroid symptoms. Take this with a grain of salt though; I tried the american WP Thyroid with not much effect, either. I have definitely felt some improvement, but it's early days. I'm gonna continue slowly bumping up my dose - I think I may just need much more thyroid than the usual 1 - 2 grains people do ok on

reliablerebel profile image
reliablerebel in reply tojconnor123

How are you going with the Tru thyroid now? Just about to start taking mine. Thanks

Not what you're looking for?

You may also like...

Dessicated Thyroid dose

Hello I have a tsh of 4 and it seems like when I reach 1 grain of dessicated thyroid I get...
arodg44 profile image

Armour v's WP Thyroid v's Westhroid tabs

Hi, my daughter has been on Armour for 1 month this coming Monday, she's not feeling any different...

Thyroid S & Levo mix.

I have been on Thyroid s for a year now and still not well. At present on 1.75 grains for the last...
princess20 profile image

Splitting EFRA Thyroid?

Yesterday my doctor prescribed 60mg (1 grain) of EFRA Thyroid as a starting dose. I read I am...
GarryB profile image

Nature thyroid

I am about to start taking nature thyroid after 5 years on levothyroxine and not doing well at all....
fishynicks profile image

Moderation team

See all
Buddy195 profile image
Buddy195Administrator
RedApple profile image
RedAppleAdministrator
PurpleNails profile image
PurpleNailsAdministrator

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.