Can any of the experts on here give me an idiots breakdown of how this may cause/influence ADHD.
I have long suspected my hypothyroidism has played a major role in my two sons development of ADHD but I’ve never been tested for any mutation.
I’m a scientist by training but most of the documents are baffling even to me!
I had a parent with type 1 diabetes and one with hypothyroidism.
Chances I have the mutation? Also, how does this affect my ongoing battle for full health? (apart from methylated supplements) What issues might I have that are directly affected by this if you get my drift.
Thank you 😊
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Murphysmum
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and thought it was quite helpful. (Be aware I'm not medically trained.)
(Added later - I've written this with your kids in mind, sorry, I went off in the wrong direction. I didn't read your post carefully enough.)
Based on that link I would have thought that supplementing with a Vitamin B Complex containing activated B vitamins would be a good start. I would probably add in vitamin C just because it seems to be helpful to so many people. Note that some people end up with low potassium when they supplement high doses of vitamin B12. Don't supplement for this, just make sure that your children eat some foods which are rich in potassium.
Biotin, which is an ingredient in many B Complex supplements, has a bad effect on some testing protocols - it distorts the test in some way and changes results. This can be a problem, so make sure that any supplements containing biotin are stopped for 5 - 7 days before blood testing. The supplement can be restarted after blood samples have been taken for testing.
You can do private blood testing with some companies, without requiring a referral from a doctor. Medichecks won't test anyone under the age of 18. I think there is a company that will test children but I'm not certain which company it is. Perhaps SeasideSusie would know. Which tests would be useful for your children is something you could ask us if you decided to test them.
The Igennus product has a daily dose of 2 tablets per day, but obviously you could tailor the dose and give your kids one a day or two a day as necessary. Or you could only give them one on certain days of the week. Obviously, you don't have to take the maximum dose every day of the week, although I'm sure the manufacturer would love it if you did. The Thorne and Jarrow products are supposed to be dosed at one a day. Again you could tailor the dose and only take it certain days of the week.
MTHFR would result in reduced DNA methylation and hence reduced gene in a number of systems including neurotransmitter production. Recent studies are more positive on a connection to ADHD: nature.com/articles/s41398-...
The MTHFR defect is quite common but genetic testing is the only way to be sure it’s relevant to your struggles. Shooting in the dark with supplements is not advised.
Sunflower lecithin is a good source of beneficial phospholipids, if you’re trying to augment the methylation cycle.
Here’s a fairly concise overview of impacts of the MTHFR defect:
I have a colleague with Hashi's and one of her sons has ADAH. She strongly suspects her condition that was undiagnosed during pregnancy to be the cause.
I have had genetic testing and I have two copies of the “altered” MTFHR gene. What issues?
My son was born with epilepsy. He has been treated successfully and leads a normal life - super intelligent guy. From what I can put together - I should not have taken the pre-natal vitamins full of the non-methylated folic acid. No one knew - we thought folic acid was good for brain / neural tube development. I was so very faithful in taking them. (He is 40)
For me the issues are, foremost and primarily: anxiety, and weight gain - probably due to fatty liver disease / poor methylation - which leads to chronic overload of toxins. When I take methylated B’s (and yes Jarrows is one of my favorites), anxiety decreases rapidly - as in within the hour! It takes longer to see any decrease in swelling around the middle - weeks.
If only taking care of my health was all I had to do, right? (How counter intuitive does that sound?!?). So, living life to the full and at light speed still at 62, issues compound daily. If I have wine, if I eat gluten, dairy, preservatives, etc. (and it happens) what does the poor methylation process leave me with? Constant ringing in the ears, (did I mention fatty liver?) anxiety, which does not lend itself to focused thinking - distraction comes easily. And somehow, I have what Drs say is only “mild” Hashimotos. (I take 1.5 grains of NatureThroid per day - for the last 30 years.)
The best scientific publication that I have found is the book: Dirty Genes by Dr. Ben Lynch. He explains many things, including how to assist this all important methylation process.
Other issues? My whole family (father, paternal aunts, etc,) died in their 50s from heart disease. Liver, inflammation, etc. contributes to heart disease. New research is coming out showing how the thyroid is connected to heart attacks, high blood pressure, etc. Here in the US, they are beginning to use T3 in the emergency rooms to help heart attach victims. They are amazed at how well it works. (Imagine that)
Eating “clean” is the single most important thing we can do with MFTHR, and yet it is almost impossible to do in our modern society of fast food / pre-packaged food “products”.
Learn all you can about this genetic variation - there are other genetic variations as well ( My Dr insists that it not be referred to as a genetic “defect”?!)
Of course, we may well find out, one day very soon, that all disease is rooted in genetic variations and be treated in very different ways. (This will become known as the dark ages of medicine). Not in my life time will genetic treatment come (most probably). So, I have all y’all and we have each other. Sharing info, learning and trying valiantly to treat ourselves in the meantime. There are some cutting edge Drs out there, making a difference keeping up with science, bravely facing a gauntlet of their peers for blazing trails. I found one - and it is truly a whole new world. Insurance companies kick them out, and they must operate in a cash only basis. Who can afford that? But that is yet another issue we, with successfully treated MFTHR variations must face.
Was it your male parent with diabetes and female parent with thyroid ? Are you all able to take the sun. any calcium issues ? Thanks
Bio resonance check up ( with Asyra instrument) by natural MD showed that I have MFTHR too. Did not do much about that , but my health is much improving with addressed pathogens , mould and heavy metals many info lately from MDs as Sayer Li ( Greenmedinfo) and dr Group ( Global Healing Centre) insisit that Hashimoto ( as many chronic illnesses ) is due to toxicity ..Taking Milk Thistle complex tincture by Vogel and Fulvic and Humic acid ( good brand ) and some wormwood and black walnut temporary tp address pathogens really helped a lot and my sleep well improved , energy and mood is so much better. Black eye circles disappeared.
Also occasionally I took Diatomaceous Earth to swipe toxins from colon and few colonic hydrotherapies .
Selenium also helped a lot as I was advise bu GHC , dr Groups’ team in an email ans sent their e book.
They also warned not to take any iodine supplement for Hashimoto , as it stores in thyroid nodules , makes them grow and mutate.
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