I know , it’s probably daft but I’ll ask anyway.
1) How does the pituitary gland send a message to the thyroid to alter t4 etc if you don’t have a thyroid
2) I’m staying on 100mcg as I said before but now when I take (in evening now not morning) it makes me feel nauseous why do you think that is, should I split the dose. Gp said I feel like that because I’m over medicated but on here I’m told I’m not.
If you have no thyroid at all, the dialogue between pituitary and body is entirely through controlling the body cells enzyme activity that converts T4 to T3. It does so through a TSH control mechanism directly concerned with how much and how active are the body's conversion of T4 to the active T3.
Now you have lost me completely. Sorry
Well simply the pituitary can't influence the thyroid if it isn't there. The T4 you take is the only source and the body converts this to T3. The pituitary isn't directly involved at all but is a bystander.
So does that mean, in this instance, that it is irrelevant as there is no thyroid to stimulate ?
So long as FT3 is well in range, what happens to TSH is much less important. Neither TSH nor FT4 are good diagnostics for T4 therapy. Or for combined therapy for that matter.
I’m a poor converter so I need it to go up to be able to take t3, my t4 is reasonable
Sorry, I've just replied to myself, please check your post, and I'll check my T3 level !!
Lol
Ironic really, as I'm starting to feel like an old broken record !
As long as you don’t look like one you will be fine. 😂
Thank you, then, as I think I thought !!!
When without a thyroid it's essential to be monitored on T3 and T4 blood tests -
T3 is the essential active hormone -
The NHS is in total denial and choosing to continue to follow guidelines that are not fit for purpose and treating us with contempt.
Thank you
Hey there again,
Since you do not have a working thyroid you have " lost " the known natural thyroid production of :- T1, T2, T3, T4, and calcitonin.
It is thought that a fully functioning working thyroid would be supporting you on a daily basis with approximately :- 100 T4 + 10 T3.
Your T4 needs to be high, or even over range, to be able to convert to a level of T3 you might find acceptable and that gives you back your " wellness ".
Your conversion maybe compromised if your ferritin, folate B12 and vitamin D are not optimal in the ranges.
Ultimately, even having all the above in place, you have " lost " that amount of T3 your thyroid produced, and it just seems logical to me, that people who have had a medical intervention and their thyroid surgically removed or ablated in situ with RAI should have both T3 and T4 on the prescription for if, and possible when, needed.
Our bodies run on T3, not a TSH or a T4 reading.
I read most people need about 40-50 T3 daily, to continue to have some QOL.
So, if on monotherapy with Levothyroxine and without a thyroid you have been automatically down regulated by about 20% of your potential well being, as you will have " lost that little bit of T3 " that your thyroid once produced.
I hope that makes some sense, and understand that the question follows on from your previous post from yesterday.
I appreciate there is a lot to take in and understand how hard this all can be when struggling with the brain fog of undermedication for hypothyroidism.
Why the nausea when taking Levo, I didn’t feel like this before, do you think the dose I’m on(100mcg) is adequate or does it mean I need an increase, or.........Does it mean I’m a pain in the A—- keep moaning, head fuzzy as well, OH B......s
I don't know - maybe the fillers - is it worth splitting and taking same dose but at either end of the day - what brand are you taking as I think many people on here have expressed dislike with certain brands, maybe someone will " chip in " or alternatively put your brand into the search engine and see if anything comes back - apart from your own post, if anything like me this morning !!
Don’t worry Iv done that myself on probably more than one occasion
What brand of Levothyroxine are you currently taking?
Which other brands have you tried?
100mcg is not a high dose if you have no thyroid
When under medicated low stomach acid is common. This could be causing nausea
What are your vitamin levels like?
Im On mercury pharma, when they suggested alternate days of 75 that was the dreaded Treva but I didn’t take that for more than a couple of days then went back to mp. Just wondered if some food an hr after may help plus the fact I keep going hot (flushes like) but past menopause
Vitamins not too bad the D is the one I need to get up more but I’m using the spray for that and doubling the dose. I have omeprazole for stomach but haven’t taken it for a while as I didn’t want to much anything up but now you saying that I do on and off get burning sensation in stomach. I put my last bloods up but didn’t do tsh so I’m just going to pick it up now then I’ll post again
Sorry the GP hasn’t put it up so receptionist can’t print it off, I have to try tomorrow
Vast majority of hypothyroid patients have low stomach acid not high acid
Omeprazole is to treat high acid
Low stomach acid has very similar symptoms but totally different Treatment
Thousands of posts on here about low stomach acid
healthunlocked.com/search/p...
Low stomach acid can be cause of heartburn
drknews.com/good-thyroid-he...
thyroidpharmacist.com/artic...
stopthethyroidmadness.com/s...
chriskresser.com/the-thyroi...
I do suffer from reflux
Atrophic Thyroiditis?
Cushings and Thyroid 
No thyroid
Living with no thyroid
