Injecting Eutroxsig Levothyroxine tablets

[simon2003]

I've had bad results taking these tablets orally. Am considering injecting a tablet. I'll probably use a micron filter. Has anyone had an experience similar they can share?

[MaisieGray]

That sounds an unwise thing to do, to me. Drugs are designed to be taken in the way prescribed, for a reason - their pharmacokinetics ie their absorption, distribution, metabolism, and excretion, are fundamental to how they will be utilised by and/or excreted from the body, and changing how you take in a drug from how it is intended that you should, means that potentially you impact any or all of those factors and can't know how it will affect you.

And if you are filtering the solution/dilution to trap residual lumps of the active ingredient, you can't know exactly what dose you are taking.

[greygoose]

It might be better to concentrate on finding out why you have bad results with levo. Is it a conversion problem? And absorption problem? An under-medication problem? Or what?

[Hay2016]

No, not something to consider without DR discussion and I feel it would be an emphatic no.

Try different brand, liquid oral Levo.

Post results and more details and someone will come up with some tips or help.

[helvella Administrator Thyroid UK]

If that were an acceptable approach, there would not be specific injectable forms of levothyroxine.

I had been going to link to information about them but it appears that both the British National Formulary and Electronic Medicines Compendium no longer list any. It is at least mentioned here:

Myxoedema coma requires emergency treatment in hospital. It's usually treated with thyroid hormone replacement medication given directly into a vein.

nhs.uk/conditions/underacti...

I wouldn't consider injecting a tablet. Far too risky.

Most of the available information about injecting tablets concerns abuse. I suspect that levothyroxine has rarely been tried as a self-prepared injection. For that reason there could be specific unexpected dangers.

[SlowDragon Administrator]

More likely you need to try different brand of Levothyroxine

Or vitamin levels are extremely low

How much Levothyroxine are you currently taking?

Do you have autoimmune thyroid disease also called Hashimoto's? If so gut issues are common.

[simon2003]

Yes I have Hashimotos, but I've since started taking Levothyoxine again. I didn't end up Injecting any levothyoxine tablets. The first month of levothyoxine therapy left me psycologically impaired so I quit them. I took a 4 week break and now they're working really well, I guess they had some nasty depression side effects the first time i ever took them. No need to shoot them up, there's an injectable version, but it gets put in a 5 minute dripline. I'm just taking it orally.