Thyroid Genetic testing profile £99 in sale that includes report Blue Horizon

[Pascha1]

bluehorizonmedicals.co.uk/t...

[Hashi-Monster]

That’s a bargain... I paid a lot more for mine

[Pascha1 in reply to Hashi-Monster]

i paid 169 I think for just the dio2 gene

[Pascha1 in reply to Hashi-Monster]

ON the blue horizon you get 1 thyroid panel for was £159.00 NOW £99.38 was

•DNA Blue Genetic Traits Test

•DNA Blue Thyroid Genetics

•DNA Blue Well Woman Genetic Report

*Unfortunately this offer cannot be used in conjunction with any other offer, this includes all of our DNA profiles*

DescriptionFor the month of October we are offering you the opportunity to purchase any DNA test and report for £99

or all three DNA tests for £199 (usually £530)

1;

DNABlue Genetic Traits Report which uncovers predispositions to:

Lactose and gluten intolerance

Digestive upsets

Weight gain with specific foods and habits

Increased need for particular vitamins / minerals

Imbalanced blood sugar

Appetite dysregulation

Histamine intolerance

Increased inflammation

Ability to deal with stress

Likelihood of high blood pressure

Ideal exercise type

Increased tendon and ligament injury

Poor alcohol detoxification

Slow caffeine metabolism

Sleep difficulties

Accelerated cellular ageing

Increased need for antioxidants

2.

DNAblue Thyroid Report which uncovers predispositions to:

Autoimmune thyroid conditions

Hypothyroidism / hyperthyroidism

Poor conversion of thyroid hormones (T4 to T3)

Reduced clearance of reverse T3 (rT3)

Poor TSH signalling

Indirect thyroid disruption due to stress and / or inflammation

3.

WellWoman DNA Report which uncovers predispositions to:

+++++++++++++++++++++++++++++++++++++++++++++++++

Oestrogen dominance - PMS, heavy periods, mood swings etc.

Hormonal imbalances

Oestrogen-linked conditions

High oestrogen receptor activity

Poor detoxification of oestrogen

Free radical damage

Poor methylation

Blood clotting

Increased “bad’ cholesterol

Cardiovascular risks

Increased need for antioxidants

Specific nutrient needs

Pathology SampleBlood

Target Turn Around Time in working days4 Weeks

Laboratory NotesBecause of the potential for interference with test results, samples should not be taken from patients taking BIOTIN in excess of 5 mg per day until at least 8 hours following the last biotin dose

Sample ContainersSwab

GP ReferralYes Included

Reviews

Blood Test Explanied

[Naomi8]

Thank you so much for posting this!I have been preparing to order a D102 test.I am due to do an active B12 test with homocysteine & other factors etc in November,after four months off B12 supplementation,so the costs really mount up.

Just ordered my Genetic test.

[Pascha1 in reply to Naomi8]

I got one Gp to give me homocysteine blood test and the nurse wouldn't do it i was fuming, that was a gp that normally works at our sister branch, my gp won't do them Grr I hate that nurse over riding last drs instructions They also have a MMA urine test can test vitamin B12 deficiency better than the B12 tests I think it shows what you have more accurately but is over 100 private

[SlowDragon Administrator in reply to Pascha1]

This one available

nutris.viapath.co.uk/pages/...

[Pascha1 in reply to SlowDragon]

Thank You SlowDragon This is very useful for me . I will get them tested in about 6 weeks B12 Ive not taken the supplements for about 4 weeks now, this is very reasonable for all the tests Thank you xx

[Naomi8 in reply to Pascha1]

A few years ago I got my GP to agree to do a FT3 test.The lab refused to do it.Got it on the NHS eventually,when I re-located.

Just re-located again & about to book my first thyroid panel with the new practice.Will they understand about T3?Will the lab agree?This is what we have to put up with,amongst other things!

[Pascha1 in reply to Naomi8]

Some Gps seem to get it done others don't, so its a bit of pot luck to get it done,,

You could say to the GP you dont feel right if the bloods look normal and ask nicely if they will do T3 test, they might do it then the lab won't test it.. its a nightmare tbh x

[Pascha1 in reply to Naomi8]

I’m doing that b12 homocysteine etc is that from st Thomas hospital your doing that? As it’s quite reasonably priced on there x

[SlowDragon Administrator]

I don't think this specifically tests DIO2

You need to check by asking them

It's just genetic traits

Any specific DNA test has to offer counselling after.

thyroiduk.org.uk/tuk/testin...

[Pascha1 in reply to SlowDragon]

They do 3 sorts of genetic testing kits

the traits are nutritional testing,,

they do they do a thyroid genetic

well woman genetics

99 each or buy all 3 for 1.99

[Pascha1]

yes it does and these others it has a report with it as well

bluehorizonmedicals.co.uk/m...

[Kitten44]

Seems cheap! Has anyone done this? It says this is what's included:

"DIO1 - Thyroid Hormone Activation

“D1” is largely expressed in the liver and kidneys. It is responsible for the clearance of rT3 from circulation, and for facilitating the conversion of T4 to T3 in plasma and surrounding tissue. This process requires selenium and iodine for optimum function. Here we look at two variants linked to poor conversion of T4 to T3 and

reduced clearance of RT3.

DIO2 - Thyroid Hormone Activation

“D2” is importantly expressed in the central nervous system, pituitary, brown fat tissue and muscle, and responds to changes in thyroid levels. D2 is responsible for the ‘local’ conversion of T4 to T3 in the thyroid, placenta and brain. It requires selenium and iodine to function optimally. Here we look at two different variants linked to decreased T4 and low mood in certain individuals.

COMT - Inactivation of Stress Hormones and Oestrogen

COMT is one of the main inactivating enzymes of stress hormones and oestrogen in the body. COMT variants cause slow clearance of stress hormones and oestrogen leading to high oestrogen and stress hormone levels which may also be linked to thyroid hormone dysfunction.

FKBP5 - Cortisol Regulation

FKBP5 is an important stress-regulating gene responsible for lowering cortisol levels after a stress response. Variants are associated with prolonged and increased symptoms of stress, which may be due to delayed lowering of cortisol levels.

PDE8B - TSH Signalling

PDE8B is found in the thyroid but not the pituitary, and is involved in TSH signalling. It is thought that the variant decreases the response of the thyroid gland to TSH stimulation

TNF-a - Inflammation

TNF-a is an inflammatory cytokine that helps regulate the immune reaction involved in inflammation, giving rise to fever and inhibiting tumour growth. If poorly controlled, it may be implicated in a number of autoimmune disorders. Variants in TNFa are associated with overreactive immune responses and prolonged inflammation.

TSHR - Thyroid Stimulating Hormone (TSH) Receptor

The TSHR gene plays a central role in thyroid metabolism by controlling the thyroid gland’s receptivity to TSH. Variants in this gene have been linked to hyperthyroidism, particularly to Graves’ Disease (GD).

TRHR - Thyrotropin Releasing Hormone (TRH) Receptor

Responsible for the body’s receptivity to TRH which stimulates the secretion of TSH from the pituitary gland. In turn, TSH stimulates the production of thyroid hormones from the thyroid gland. TRH is an important part of the negative feedback loop that ultimately regulates thyroid hormone levels. Variants have been shown to affect TSH levels.

The information provided is strictly for educational purposes and is not intended for diagnostic or treatment purposes and should not

be used as a substitute for professional medical advice. Use the information provided solely at your own risk. If you have any concerns about your health, please consult a qualified health professional."

I'm wary of the last comment of "strictly for educational purposes and is not intended for diagnostic or treatment purposes".

Does it mean this test is in any way inferior to the other DIO2 tests available elsewhere?

[SlowDragon Administrator in reply to Kitten44]

EXACTLY my point....educational purposes only

A proper DNA test must include counselling by law

[DippyDame in reply to SlowDragon]

Trying to get my head round this...

By a proper DNA test do you mean one that tests the whole genome, opening up the possibility of revealing some nasty surprises for which counselling may be important.

I understood that the thyroid genetic tests look for markers which indicate genetic variations likely to affect thyroid patients rather than testing the whole genome.

I'm now wondering about the interpretation of " strictly for educational purposes and is not intended for diagnostic or treatment purposes"...I took it to be their way of covering themselves should any legal challenges arise.

If the test results are offered as "for educational purposes" that, I guess, indicates they are teaching or informing us about the presence, or not, of any genetic variations affecting thyroid function... but, they are also saying don't blame us should problems arise from the use of that information! We now live in a litigous society!

I don't regret having had the test done - only that I didn't get it discounted! Kitten44 I personally don't consider it inferior to any other thyroid genetic marker tests. It confirmed that I have a faulty DIO2 gene inherited from both parents.. According to research that suggests poor conversion is even greater than inheritance from one parent.

If I'm talking rubbish then I'm sure someone will tell me!

[SlowDragon Administrator in reply to DippyDame]

Be interesting to know the answer

Regenerus only test for DIO2 and you have to have counselling session at £60

Perhaps the "only intended for educational purposes" gets around the necessity for counselling, which is obviously adding to cost

[Pascha1 in reply to SlowDragon]

The have ways round it, maybe the educational thing they may even call you with the results, which would be councilng. I didn’t read that bit,

it gives you a printed report on all the genes, it looks similar to the one medich3cks did a while back but think this is cheaper, it won’t stay this price for long it’s an introduction price I think

23and me gave me 1000s of raw data, I hav3 found some seriously bad genes in me, I have over 1000 bad ones, smec early rare double ones, which sound scare6 . it’s taken me ages to research it all.l that’s worse as leaves you wondering what it actually means on some of them . X

[Naomi8 in reply to Pascha1]

I still haven't opened the "Could be scary"boxes in the 23& me genetic test I did over 2 years ago.As for the rest of the data-its overwhelming & very difficult to interpret,despite some helpful advice from members on here,on free websites that help.One of them recommended supplements to conteract the "bad"genetic tendencies,which was quite useful,though one supplement,DIM, made me as ill as if I'd had food poisoning,twice,before I binned it.

[Pascha1 in reply to Naomi8]

You should down load it soon as I heard they are stopping the down loading soon so won’t be worth having soon

Just go to doi2 in raw data it won’t tell you what’s wrong just letters , my thyroid ones were not done on 23and me. I’ve had regenerous and now I’ve done this one, just out of curiosity , I don’t look up the cancer ones