Is anyone taking Metative I - a natural supplem... - Thyroid UK

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Is anyone taking Metative I - a natural supplement for an under active thyroid?

Angie33 profile image
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Is anyone taking Metavive I (natural supplement for an under active thyroid)? If so, how are you finding it? Are you making an improvement?

My GP has been telling me for years my thyroid was fine. However, after 7 years of chronic fatigue I decided to get a private test out of desperation. I now know I have an under active thyroid which has probably lead to my adrenals being severely deplited.

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Angie33
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Clutter profile image
Clutter

Angie33,

If you are underactive your GP should prescribe Levothyroxine. What were your recent thyroid results and ranges?

Angie33 profile image
Angie33 in reply toClutter

Thanks for relplying. According to my GP my thyroid is 'satisfactory':

TSH 1.16 (0.55 - 4.78)

T4 1.3 (10-25u)

T3 4.2 (4.0 - 7.0)

However, after suffering from chronic fatigue for 7 years and at my wits end with my poor quality of life. I decided to get a private thryoid test as I read thousands of people have been misdiagnosed as GP's test ranges are antiquated.

My private test results are:

TSH 1.49 (0.27 - 4.2)

T4 11.6 (12 - 22) * low

T3 4.3 (3.1 - 6.8)

I was informed by Private Dr that I would benefit from taking Metavive I and running on a higher level of TSH, T3 and T4.

GP can't give me any pills as she reckons my thyroid is 'satisfactory'. I am tired of being told all my tests are 'satisfactory' hence I have spent a small fortune on various private tests.

My adrenals are also severly depleted as a result of my under active thyroid or it could be the other way around. No way of knowing I guess.

Clutter profile image
Clutter in reply toAngie33

Angie33,

I think there may be a typo in your NHS T4 result? Should it be 13?

GP test ranges aren't antiquated. They're updated whenever the lab updates equipment.

Your private test results show T4 is below range which means you are hypothyroid despite low-normal TSH. Your GP should be considering secondary or central hypothyroidism caused by insufficient production of bioactive TSH due to a pituitary or hypothalamic disorder. See the NICE CKS link below. I'm surprised your private GP didn't mention it. If your NHS GP still thinks your thyroid is 'satisfactory' you should change GP.

NICE CKS recommend patients with suspected central hypothyroidism are referred to endocrinology for management as investigation may also been needed to rule out sex and growth hormone deficiencies.

cks.nice.org.uk/hypothyroid...

Angie33 profile image
Angie33 in reply toClutter

Gosh, thanks so much for your feedback. I am very grateful. Oops, yeah a typo. Is should read 13.

I did read that lab ranges used for routine testing has been a controversial topic in medicine in recent years. Supposedly there is much debate and arguing as to what the actual range should be as most Dr's are still using the old standard. Either way, your feedback is valuable. I will definitely investigate futher. Thank you SO much x

Clutter profile image
Clutter in reply toAngie33

Angie33,

There is no standard range or universal range. The manufacturers calibration of the assay machinery and a mean average result of population samples in the lab's area determine the lab ref ranges.

You should show your NHS GP your private results and ask for secondary/central hypothyroidism to be considered before you start taking Metavive.

Angie33 profile image
Angie33 in reply toClutter

Thanks for elaborating. You clearly know what you are talking about! I wish you were my GP. I did show my GP my private tests she didn't say anything other than she can't give me thyroxine as a result of their tests being 'satisfactory' I do have an appointment next week to ask for a secondary/central hypothyrodisims to be considered, thanks to you :-) I'm thinking taking metavive can't be harmful if even my GP levels are pretty low. Running on the high end of the scale may be a good thing. What I wouldn't give to no longer spend most of my life housebound. I guess the flu virus I caugh in Jan has set me back quite a bit.

Clutter profile image
Clutter in reply toAngie33

Angie33,

If you take the Metavive 1 it will skew the results of any thyroid tests your GP may want to do. If your GP refuses to consider secondary/central hypothyroidism then see another GP or change GP practice.

1 x Metavive 1 won't be harmful but it won't be enough to improve your thyroid levels either.

Angie33 profile image
Angie33 in reply toClutter

My GP did the tests before I started on Metavive I. I have been informed I need to be on at least 60mg each day which will probably mean progressing to Metavive II. Not sure. I will persevere as to be honest it is the only hope I have right now of maybe improving my health. I guess it will take a few months before I notice a big difference. Hopefully :-)

Clutter profile image
Clutter in reply toAngie33

Angie33,

If you are determined to self-medicate you should be aware that you will have to stop taking Metavive if you want to pursue a NHS diagnosis at any time.

You can start with 1 x Metavive I to see how you tolerate it. It won't be enough and you will need to increase dose at 2 week intervals until your TSH is 0.2 - 1.0 with FT4 and FT3 halfway through range or higher.

Angie33 profile image
Angie33 in reply toClutter

Thank you for all your advice. Really is much apprecaited.

I think I will request another test after 2 months on metavive and one month on adrenavive III.

It's the first lead in 7 years so it's at least something to go by.

Well, other than being diagnosed with chronic fatigue a few years ago.

I am hopeful :-) I guess I just have to be very patient. I will continue to monitor my body temperature. When I am nearer 37 degrees I will request another private thyroid test to see what dose suits me x

Clutter profile image
Clutter in reply toAngie33

Angie33,

Temperature is not a guide to hypothyroidism or euthyroidism. A sudden spike in temperature can indicate overmedication but equally it may be due to a fever.

Angie33 profile image
Angie33 in reply toClutter

Thanks! Yeah I was informed by my GP that a gradual increase in temperature, bringing me up to 37 degrees, will be a good gauge of when to stop increasing my medication. I am still floored from the flu virus I caught beginning of January too.

Clutter profile image
Clutter in reply toAngie33

Angie33,

Blood tests are a better guide to optimal dosing. Temperature doesn't always rise.

Angie33 profile image
Angie33 in reply toClutter

Oh gosh, seriously. My core body temperatue is 35.5 degrees. I was told that is very low to be constant and that is should increase as I increase the does of metavive I. I have an appointment with my GP on monday to discuss secondary/central hypothyroidism. Can I ask, do you have a medical background? You have more valuable information than my GP which I am very grateful for :-)

Clutter profile image
Clutter in reply toAngie33

Angie33,

I don't have a medical background, I've just read widely about thyroid.

If hypothyroidism is causing low temperature then it may improve when you are optimally dosed but low temperature can be caused by things other than hypothyroidism which is why blood tests are used to determine euthyroidism/hypothyroidism.

Secondary/central hypothyroidism is determined by low TSH, low FT4 and FT3 at DIAGNOSIS. Taking Metavive or other thyroid replacement will raise FT4 and FT3 and lower TSH so it will skew your thyroid results.

Angie33 profile image
Angie33 in reply toClutter

Thanks so much. If my TSH, FT4 and FT3 increase with metavive and skew my next thyroid tests which have always been via blood samples, then this will mean my thyorid is improving, which is good, yeah?

Clutter profile image
Clutter in reply toAngie33

Angie33,

No, it means Metavive is improving your TSH, FT4 and FT3 blood results which it is supposed to do, not that it is skewing your results, or that thyroid gland is improving.

Angie33 profile image
Angie33

Thanks so getting back to me, much appreciated. Is there a reason why people are substituting Metavive with Nutrithyroid? I am not suffering any side effects from metavive. I guess I am just patiently waiting for results. It has only been one month tho. I am currently on 45mg and have been advised I might be best taking at least 60mg. However, best to increase dose every 2 weeks.

I am also on Adrenavive. I'm just wondering if anyone else is taking both and curious how you are getting on? Is Nurtithyroid better?

Clutter profile image
Clutter in reply toAngie33

Angie33,

NutriThyroid and NutriAdrenal were unavailable for much of 2017 so people switch to Metavive and Adrenavive.

Angie33 profile image
Angie33

Ah, thanks Clutter. Much apprecaited

Furface profile image
Furface

I am on both Metavive and Adrenavive because NHS failed to acknowledge thyroid problem and so many symptoms preferring to keep me sick. Turns out I have been Hypothyroid all along but through not being treated, have also been rock bottom with vitamins and Adrenal Exhaustion, Oestrogen Dominance and now have many parasites as well as Streptococcus, H.Pylori and Candida. This makes absorbing anything difficult.

For me it is the difference between wanting to die as quality of life was rock bottom, sleeping 23 hours a day, with horrendous pain and then after taking Metavive, some feeling came back into my hands, then warmth, then the brain fog improved and numerous other things improved out of the 94 symptoms. Had Saliva test done which revealed me flatlining and not able to sleep at all, had an adrenal crisis where my blood sugars dropped. Was then put on Adrenavive. Gradually, I have been able to sleep again. The downside is that it takes a long time to heal the adrenals so raising your dose of Metavive is painfully slow but not for anyone including the Endo I saw the other day who said I should stop taking both of these, will I stop! (He says I am fine by the way even though I gave him copies of the private tests. He lied and omitted selective things in his report to the GP and discharged me back to his care . . . what care?)

I cannot and will not go back to being a corpse who is slowly and painfully heading towards death. (In the meantime I am building up Vitamin D deficiency, rock bottom ferritin and low B12 which I have learnt will help my thyroid to function).

Angie33 profile image
Angie33

Hi Furface, thanks so much for your reply. I can sympathise with 'just existing' and having had enough! Like you I am managing to hang in there in the hope these pills will help. To be honest. That's interesting it has taken you a long time before you feel the benefit of these pills. I have only been on these for 5 weeks. I clearly need to be patient. Great news you are noticing a difference. I am led to believe I will be on these for the rest of my life.

My body temperatue is gradually increasing from around 35.5 to 35.97 on average each day so that has to be a positive sign after 5 weeks.

I have also been injecting vitamin B12 and magnesium each day for 5 weeks.

I am hopeful things are starting to look up. I guess I was just wondering roughly when I will be up and about a good bit more. Clearly 5 weeks is very early days!

Good luck with your recovery and your GP!

m7-cola profile image
m7-cola

H Angie

Because I am now considering taking Metavive I have been reading the thread you took part in last year. Can you tell me whether it has helped you and if so whether you have reached the 60mg level and are content to continue?

Both my husband and I are hypothyroid, taking T3 from Germany and improving on it. We

are not sure whether this will still be accessible after Brexit so looking for alternatives.

We are currently under an endocrinologist but would prefer to step out of the medical treadmill and look after our own health needs (as far as possible).

Hoping to hear from you.

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